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← CockpitCompetitor Analysis › XERS Xeris Biopharma Holdings, Inc.Open in the cockpit ↗

Xeris Biopharma Holdings, Inc.XERSCompetitor analysis, valuation and peers

United States · USD·Health Care›Biotechnology

Makes ready-to-use injectable and delivery technologies for hormone deficiency and endocrine drugs.

Momentum leader 99
Mkt cap
$2.77B
US dollars, full cap
Free float
95%
of shares outstanding
$/day
$35.1M
20-day average traded
Fwd P/E
67.9×
forward earnings
ROIC−WACC
+9.7 pp
WACC 8.6%
Hurdle
-37 pp
Req g minus delivered
Next earnings
124 days
10 Mar 2027
Close · USD$15.20
1D+16.2%
1W+41.9%
1M+49.2%
3M+90.2%
6M+132.8%
YTD+93.6%
1Y+54.0%
ATR %5.2%
Beta0.22
52w lowhigh0.1% off high

What Xeris Biopharma does

Makes ready-to-use injectable and delivery technologies for hormone deficiency and endocrine drugs.

Earns from selling three branded drugs in the US, mostly through wholesalers and pharmacies, with insurers deciding coverage. Gvoke serves diabetes, a large patient group, while Recorlev and Keveyis treat rare conditions with few prescribers. The 2021 merger with Strongbridge Biopharma brought in the two rare-disease drugs.

Products and services

  • Gvoke (ready-to-use glucagon, severe hypoglycemia)
  • Recorlev (Cushing's syndrome)
  • Keveyis (rare periodic paralysis)

Customers

  • Endocrinologists
  • Diabetes patients/caregivers

Where it sits in the supply chain

  • Health Care
  • Biotechnology
  • Injectable drug delivery for endocrine…

What could go right

  • Gvoke market share growth vs nasal/injectable rivals
  • Recorlev commercial ramp

What could go wrong

  • Competitive glucagon/endocrine drug market
  • Small-cap financing and dilution risk

Moat: narrow (IP / patents, process know-how). Proprietary non-aqueous formulation technology avoids the reconstitution steps needed by rival products.

Headquarters: Chicago, Illinois, US · Founded: 2005 · Employees: 435

Named competitors

Xeris Biopharma at a glance

Size Xeris Biopharma (XERS) is a United States Health Care company (Biotechnology) with a market value of $2.77B, the 1594th largest of 3,117 United States companies the cockpit tracks. Shares closed at $15.20 on 6 Nov 2026.

Performance Over six months the shares gained 132.8%, against -3.9% for the median peer and -1.1% for the United States market (cap-weighted) — 2nd highest of 20 in its peer set.

Growth Revenue grew 36.3% over the last twelve months (peer median +2.8%); the operating margin is 10.9% (peer median -19.5%).

Valuation It trades at 67.9× forward earnings against a peer median of 36.8× (4th most expensive of 8).

Price implies For today's price to make sense, revenue must grow about 33% a year for seven years (Req g). Recent delivered growth is +70%, so the hurdle is -37 pp: the price already allows for a slowdown.

Capital Return on invested capital runs 9.7 points above its cost of capital (8.6% WACC).

Backlog Backlog (remaining performance obligations) was $6.20M at 30 Sep 2026 — 0.0 years of trailing revenue. Backlog detail →

Short interest Short interest is 4.4% of the free float (15 Oct 2026).

Next results Next results expected around 10 Mar 2027 (exchange calendar; dates can move).

Relative performance

10015020025011 May 202611 Aug 20266 Nov 2026XERS 248Peer median 95
Six months, rebased to 100: Xeris Biopharma against the median of its 20 peers (local-currency closes).

Xeris Biopharma financials

Reported figures in USD; fiscal year ends 2025-12-31. TTM = trailing twelve months.
TTMFY2025FY2024FY2023FY2022
Revenue$335M$292M$203M$164M$110M
Revenue growth—+44%+24%+49%—
Gross profit$280M$238M$155M$124M$76.8M
EBITDA$49.4M$37.6M-$21.0M-$30.9M-$67.8M
Net income-$17.2M$554,000-$54.8M-$62.3M-$94.7M
Free cash flow$55.7M$27.9M-$37.8M-$50.5M-$103M
Capital expenditure$938,000$696,000$868,000$2.26M$524,000
Total debt$289M$258M$271M$229M$198M

Quarterly statements and history in the cockpit →

Xeris Biopharma competitor charts

The default views of Competitor Analysis ▸ Charts, drawn from the same data. Open them in the cockpit to change the axes, pin companies and read every value.

Performance: 6-month against 1-month return

0%+100%-25%0%+25%+50%688278BEAM300142ADMA6887300255XNCRRUBICON9688BAVARCUS6919PVLA028300MBXPHVSDNLIXERS6-month return →1-month return →
Up and to the right = strong over both horizons. Xeris Biopharma is the large dot.

Fundamentals: revenue growth against valuation

-20%0%+20%+40%0×200×400×688278300142ADMARUBICONBAVA300676TLXXERSRevenue growth (TTM) →Forward P/E →
Further right = faster growth; higher = more expensive. The dashed lines are the peer medians. Xeris Biopharma is the large dot.

Capital: growth delivered against growth the price implies

0%+20%+40%+60%0%25%50%75%688278300142ADMABAVAXERSGrowth delivered (Del g) →Growth the price implies (Req g, 7 yrs) →
Above the diagonal = the price needs more growth than the company has been delivering; below = the price already allows for a slowdown. Xeris Biopharma is the large dot.

Xeris Biopharma competitors and peer comparison

Head to head with its named competitors (XERS vs LLY vs NOVO-B.CO)
CompanyMarket cap6M returnRevenue growthOp. marginForward P/EReq g
Xeris Biopharma XERS$2.77B+133%+36%11%67.9×33.3%
Lilly (Eli) LLY$1.27T+43%+46%51%28.9×5.9%
Novo Nordisk A/S NOVO-B.CO$190B-7%+6%48%11.9×0.1%

How Xeris Biopharma compares with its peers

Peer set: Industry: the same industry and sector in any market, nearest in size. This is the same default set the interactive Competitor Analysis opens with.

Xeris Biopharma against its 20 peers (data as of 6 Nov 2026)
MeasureXERSPeer medianRank in peer set
1-month return+49.2%-6.6%highest of 21
6-month return+132.8%-3.9%2nd highest of 20
Distance from 52-week high-0.1%-30.1%highest of 21
Revenue growth (TTM)+36.3%+2.8%3rd highest of 17
Operating margin10.9%-19.5%5th highest of 17
Forward P/E67.9×36.8×4th most expensive of 8
Growth the price implies (Req g, 7 yrs)33.3%-0.2%most demanding of 5
Growth delivered (Del g)+70.2%+31.7%highest of 5
Hurdle (Req g minus delivered)-36.9 pp-32.5 pp2nd least demanding of 5
ROIC minus cost of capital+9.7 pp-10.2 pp3rd highest of 15
EV / EBITDA59.5×37.0×3rd cheapest of 5
Net debt / EBITDA3.4×0.3×3rd most indebted of 6

Peer table

Peer set: Industry: the same industry and sector in any market, nearest in size
CompanyMarketMarket cap6M returnRevenue growthOp. marginForward P/EReq gDelivered g
Xeris Biopharma XERSUnited States$2.77B+133%+36%11%67.9×33.3%+70.2%
Xiamen Amoytop Biotech 688278.SSChina$2.76B-23%+18%27%16.2×0.5%+36.0%
Beam Therapeutics BEAMUnited States$2.73B-18%+163%-268%n/an/an/a
Walvax Biotechnology 300142.SZChina$2.71B-12%-23%5%381.7×31.3%-3.8%
ADMA Biologics ADMAUnited States$2.85B+56%+8%42%15.7×-0.8%+64.6%
Sunshine Lake Pharma 6887.HKHong Kong$2.85B-9%+20%-3%n/an/an/a
Hebei Changshan Biochemical Pharmaceutical 300255.SZChina$2.68B-52%0%-25%n/an/an/a
Xencor XNCRUnited States$2.66B+178%-29%-206%n/an/an/a
Rubicon Research RUBICON.NSIndia$2.91B+74%+37%21%77.2×n/an/a
Zai Lab 9688.HKHong Kong$2.92B+13%+5%-59%n/an/an/a
Bavarian Nordic A/S BAVA.CODenmark$2.93B+27%-3%16%17.1×-2.0%+27.4%
Arcus Biosciences RCUSUnited States$2.59B-28%-55%-415%n/an/an/a
Evopoint Biosciences 688837.SSChina$2.58Bn/an/an/an/an/an/a
Caliway Biopharmaceuticals 6919.TWTaiwan$3.01B-37%-54%-6,983%n/an/an/a
Palvella Therapeutics PVLAUnited States$2.53B+45%-100%n/an/an/an/a
HLB 028300.KSSouth Korea$3.06B-49%+29%-96%n/an/an/a
MBX Biosciences MBXUnited States$2.47B+25%n/an/an/an/an/a
Pharvaris PHVSUnited States$2.41B+14%n/an/an/an/an/a
Denali Therapeutics DNLIUnited States$3.22B+2%n/a-2,488%n/an/an/a
BGI Genomics 300676.SZChina$2.39B-4%0%-14%142.2×n/an/a
Telix Pharmaceuticals TLX.AXAustralia$3.22B-6%+27%-1%36.8×n/an/a

Xeris Biopharma backlog

Xeris Biopharma reported $6.20M of remaining performance obligations at 30 Sep 2026 and up 24% from the previous quarter. That is 0.0 years of trailing revenue already under contract. Book-to-bill last quarter: 1.01.

Questions

Who are Xeris Biopharma's main competitors?
Named competitors: Eli Lilly (Baqsimi) (LLY), Novo Nordisk (NOVO-B.CO). The cockpit's measured peer set (industry) also includes Xiamen Amoytop Biotech (688278.SS), Beam Therapeutics (BEAM), Walvax Biotechnology (300142.SZ), ADMA Biologics (ADMA), Sunshine Lake Pharma (6887.HK), Hebei Changshan Biochemical Pharmaceutical (300255.SZ).
Is Xeris Biopharma expensive compared with its peers?
On forward p/e it trades at 67.9× against a peer median of 36.8×, 4th most expensive of 8 in its peer set. For today's price to make sense, revenue must grow about 33% a year for seven years (Req g). Recent delivered growth is +70%, so the hurdle is -37 pp: the price already allows for a slowdown.
How has Xeris Biopharma stock performed?
Over six months to 6 Nov 2026 the shares returned +132.8% against -3.9% for the median peer; over one year +54.0%.
What is Xeris Biopharma's backlog?
Xeris Biopharma's remaining performance obligations (contracted revenue not yet recognised) were $6.20M at 30 Sep 2026.

How these numbers are made. Returns are close-to-close in local currency. Revenue growth and margins are trailing twelve months. Req g is the revenue growth that today's enterprise value requires for seven years at the company's own cost of capital; Delivered g is what it actually grew; the gap is the hurdle (honest precision about ±8 points, so read the ranking more than the decimal). No fair values, price targets or analyst ratings are shown, by design. Method and validation.