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← CockpitCompetitor Analysis › MBX MBX Biosciences, Inc.Open in the cockpit ↗

MBX Biosciences, Inc.MBXCompetitor analysis, valuation and peers

United States · USD·Health Care›Biotechnology

Develops long-acting peptide therapies for endocrine and metabolic diseases including hypoparathyroidism and obesity.

Momentum neutral 49
Mkt cap
$2.47B
US dollars, full cap
Free float
63%
of shares outstanding
$/day
$29.4M
20-day average traded
Fwd P/E
n/m
no positive forecast
ROIC−WACC
n/a
WACC 6.4%
Hurdle
n/a
no reverse DCF
Next earnings
136 days
22 Mar 2027
Close · USD$51.35
1D+6.0%
1W-8.1%
1M-3.6%
3M-22.4%
6M+25.4%
YTD+62.8%
1Y+127.7%
ATR %7.0%
Beta1.13
52w lowhigh29.3% off high

What MBX Biosciences does

Develops long-acting peptide therapies for endocrine and metabolic diseases including hypoparathyroidism and obesity.

Has no product to sell, so it is funded by money raised from investors, and any future income would come from selling its own drugs or licensing them to a larger drugmaker. Its platform engineers peptides to be dosed less often, such as once weekly. It listed in 2024.

Products and services

  • MBX 2109 (hypoparathyroidism)
  • MBX 1416 (obesity, GLP-1/GIP)

Customers

  • Endocrinologists (post-approval)

Where it sits in the supply chain

  • Health Care
  • Biotechnology
  • Peptide therapeutics for endocrine…

What could go right

  • Hypoparathyroidism pivotal data
  • Entry into the large obesity/metabolic market

What could go wrong

  • Clinical trial failure risk
  • Crowded GLP-1/obesity competitive field

Moat: none (IP / patents). Clinical-stage biotech with proprietary long-acting peptide chemistry but no approved products yet.

Headquarters: Carmel, Indiana, US · Founded: 2019 · Employees: 63

Named competitors

MBX Biosciences at a glance

Size MBX Biosciences (MBX) is a United States Health Care company (Biotechnology) with a market value of $2.47B, the 1660th largest of 3,117 United States companies the cockpit tracks. Shares closed at $51.35 on 6 Nov 2026.

Performance Over six months the shares gained 25.4%, against -10.8% for the median peer and -1.1% for the United States market (cap-weighted) — 7th highest of 20 in its peer set.

Short interest Short interest is 9.2% of the free float (15 Oct 2026).

Next results Next results expected around 22 Mar 2027 (exchange calendar; dates can move).

Relative performance

10015011 May 202611 Aug 20266 Nov 2026MBX 128Peer median 93
Six months, rebased to 100: MBX Biosciences against the median of its 20 peers (local-currency closes).

MBX Biosciences financials

Reported figures in USD; fiscal year ends 2025-12-31. TTM = trailing twelve months.
TTMFY2025FY2024FY2023FY2022
Revenue$0$0$0$0$0
Revenue growth—————
Gross profit-$303,000-$248,000-$244,000-$157,000-$56,000
EBITDA-$118M-$97.8M-$68.0M-$35.2M-$25.1M
Net income-$104M-$87.0M-$61.9M-$32.6M-$26.1M
Free cash flow-$85.2M-$81.9M-$55.6M-$32.1M-$23.6M
Capital expenditure$2.53M$1.93M$874,000$129,000$441,000
Total debt$3.34M$598,000$213,000$518,000$527,000

Quarterly statements and history in the cockpit →

MBX Biosciences competitor charts

The default views of Competitor Analysis ▸ Charts, drawn from the same data. Open them in the cockpit to change the axes, pin companies and read every value.

Performance: 6-month against 1-month return

0%+100%-25%0%+25%+50%PHVSPVLA300676RCUSCLDXZEALXNCRCOAG300255SEPNVIMIAN300142688520BEAMXERSAUPHMBX6-month return →1-month return →
Up and to the right = strong over both horizons. MBX Biosciences is the large dot.

MBX Biosciences competitors and peer comparison

Head to head with its named competitors (MBX vs ASND vs NOVO-B.CO vs LLY)
CompanyMarket cap6M returnRevenue growthOp. marginEV / SalesReq g
MBX Biosciences MBX$2.47B+25%n/an/an/an/a
Ascendis Pharma A/S ASND$16.0B+8%+128%10%12.8×36.4%
Novo Nordisk A/S NOVO-B.CO$190B-7%+6%48%4.0×0.1%
Lilly (Eli) LLY$1.27T+43%+46%51%15.2×5.9%

How MBX Biosciences compares with its peers

Peer set: Industry: the same industry and sector in any market, nearest in size. This is the same default set the interactive Competitor Analysis opens with.

MBX Biosciences against its 20 peers (data as of 6 Nov 2026)
MeasureMBXPeer medianRank in peer set
1-month return-3.6%+1.3%8th lowest of 21
6-month return+25.4%-10.8%7th highest of 20
Distance from 52-week high-29.3%-33.2%9th highest of 21

Peer table

Peer set: Industry: the same industry and sector in any market, nearest in size
CompanyMarketMarket cap6M returnRevenue growthOp. marginEV / SalesReq gDelivered g
MBX Biosciences MBXUnited States$2.47B+25%n/an/an/an/an/a
Pharvaris PHVSUnited States$2.41B+14%n/an/an/an/an/a
Palvella Therapeutics PVLAUnited States$2.53B+45%-100%n/an/an/an/a
BGI Genomics 300676.SZChina$2.39B-4%0%-14%3.7×n/an/a
Evopoint Biosciences 688837.SSChina$2.58Bn/an/an/a67.9×n/an/a
Arcus Biosciences RCUSUnited States$2.59B-28%-55%-415%17.1×n/an/a
Celldex Therapeutics CLDXUnited States$2.35B-12%-97%-206,220%10,375.3×n/an/a
Zealand Pharma A/S ZEAL.CODenmark$2.32B-32%-49%51%0.3×n/an/a
Xencor XNCRUnited States$2.66B+178%-29%-206%22.6×n/an/a
Hemab Therapeutics COAGUnited States$2.29B+95%n/an/an/an/an/a
Hebei Changshan Biochemical Pharmaceutical 300255.SZChina$2.68B-52%0%-25%21.9×n/an/a
Septerna SEPNUnited States$2.28B+105%+13,520%-57%19.5×18.7%n/a
Vimian VIMIAN.STSweden$2.26B+41%+8%19%4.9×12.5%+44.5%
Walvax Biotechnology 300142.SZChina$2.71B-12%-23%5%10.3×31.3%-3.8%
Sinocelltech 688520.SSChina$2.25B-23%-40%-75%15.6×n/an/a
Beam Therapeutics BEAMUnited States$2.73B-18%+163%-268%13.2×n/an/a
SKBS 302440.KSSouth Korea$2.22B-11%+23%-25%4.5×n/an/a
Xiamen Amoytop Biotech 688278.SSChina$2.76B-23%+18%27%4.7×0.5%+36.0%
Immunome IMNMUnited States$2.21B-17%-100%n/an/an/an/a
Xeris Biopharma XERSUnited States$2.77B+133%+36%11%8.8×33.3%+70.2%
Aurinia Pharmaceuticals AUPHUnited States$2.21B+8%+21%45%5.5×5.1%+41.4%

Questions

Who are MBX Biosciences's main competitors?
Named competitors: Ascendis Pharma (ASND), Novo Nordisk (NOVO-B.CO), Eli Lilly (LLY). The cockpit's measured peer set (industry) also includes Pharvaris (PHVS), Palvella Therapeutics (PVLA), BGI Genomics (300676.SZ), Evopoint Biosciences (688837.SS), Arcus Biosciences (RCUS), Celldex Therapeutics (CLDX).
How has MBX Biosciences stock performed?
Over six months to 6 Nov 2026 the shares returned +25.4% against -10.8% for the median peer; over one year +127.7%.

How these numbers are made. Returns are close-to-close in local currency. Revenue growth and margins are trailing twelve months. Req g is the revenue growth that today's enterprise value requires for seven years at the company's own cost of capital; Delivered g is what it actually grew; the gap is the hurdle (honest precision about ±8 points, so read the ranking more than the decimal). No fair values, price targets or analyst ratings are shown, by design. Method and validation.