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← CockpitCompetitor Analysis › ASND Ascendis Pharma A/SOpen in the cockpit ↗

Ascendis Pharma A/SASNDCompetitor analysis, valuation and peers

United States · USD·Health Care›Pharmaceuticals: Major

Danish biotech using its TransCon sustained-release technology for growth-hormone and endocrine-disease drugs.

Momentum strong 72
Mkt cap
$16.0B
US dollars, full cap
Free float
99%
of shares outstanding
$/day
$152M
20-day average traded
Fwd P/E
40.8×
forward earnings
ROIC−WACC
+1.3 pp
WACC 6.8%
Hurdle
-116 pp
Req g minus delivered
Next earnings
5 days
11 Nov 2026
Close · USD$256.82
1D+1.3%
1W+2.2%
1M+15.3%
3M+0.5%
6M+7.6%
YTD+20.4%
1Y+29.9%
ATR %2.5%
Beta0.31
52w lowhigh9.0% off high

What Ascendis Pharma A/S does

Danish biotech using its TransCon sustained-release technology for growth-hormone and endocrine-disease drugs.

Sells its medicines itself in the US and Europe to specialist doctors, and relies on partners such as Visen in China, paid through upfront, milestone and royalty payments. Its TransCon technology attaches a drug to a carrier that releases it slowly, giving long-acting dosing, and the same engine is used to build new products.

Products and services

  • Skytrofa (growth hormone deficiency)
  • Yorvipath (hypoparathyroidism)
  • Oncology/rare-disease pipeline

Customers

  • Endocrinologists
  • Pediatric specialists
  • Payers

Where it sits in the supply chain

  • Pharmaceuticals
  • Biotech
  • Endocrinology - growth hormone, rare…

What could go right

  • Skytrofa/Yorvipath share gains from convenient dosing
  • Pipeline expansion using the TransCon platform

What could go wrong

  • Reimbursement/pricing pressure in rare disease
  • Execution risk scaling multiple launches at once

Moat: narrow (IP / patents, process know-how). Proprietary TransCon prodrug technology gives longer-acting dosing than older daily therapies.

Headquarters: Copenhagen, Denmark · Founded: 2006

Named competitors

Ascendis Pharma A/S at a glance

Size Ascendis Pharma A/S (ASND) is a United States Health Care company (Pharmaceuticals: Major) with a market value of $16.0B, the 572nd largest of 3,117 United States companies the cockpit tracks. Shares closed at $256.82 on 6 Nov 2026.

Performance Over six months the shares gained 7.6%, against +3.8% for the median peer and -1.1% for the United States market (cap-weighted) — 8th highest of 21 in its peer set.

Growth Revenue grew 128.4% over the last twelve months (peer median +18.9%); the operating margin is 10.3% (peer median 23.1%).

Valuation It trades at 40.8× forward earnings against a peer median of 25.5× (6th most expensive of 20).

Price implies For today's price to make sense, revenue must grow about 36% a year for seven years (Req g). Recent delivered growth is +152%, so the hurdle is -116 pp: the price already allows for a slowdown.

Capital Return on invested capital runs 1.3 points above its cost of capital (6.8% WACC).

Short interest Short interest is 4.8% of the free float (15 Oct 2026).

Next results Next results expected around 11 Nov 2026 (exchange calendar; dates can move).

Relative performance

9010011011 May 202611 Aug 20266 Nov 2026ASND 108Peer median 105
Six months, rebased to 100: Ascendis Pharma A/S against the median of its 20 peers (local-currency closes).

Ascendis Pharma A/S financials

Reported figures in USD; fiscal year ends 2025-12-31. TTM = trailing twelve months.
TTMFY2025FY2024FY2023FY2022
Revenue$1.22B$813M$393M$288M$53.8M
Revenue growth—+107%+36%+436%—
Gross profit$1.10B$691M$333M$225M$25.7M
EBITDA$147M-$134M-$282M-$472M-$572M
Net income$867M-$257M-$409M-$520M-$613M
Free cash flow$389M$51.3M-$333M-$508M-$536M
Capital expenditure$16.9M$9.58M$1.54M$2.64M$15.2M
Total debt$515M$1.02B$887M$712M$543M

Quarterly statements and history in the cockpit →

Ascendis Pharma A/S competitor charts

The default views of Competitor Analysis ▸ Charts, drawn from the same data. Open them in the cockpit to change the axes, pin companies and read every value.

Performance: 6-month against 1-month return

0%+25%+50%+75%+100%-10%0%+10%+20%ORNAV64466885064507EXELJAZZIPNSOBI6990TORNTPHARM1801LAURUSLABS1177ZYDUSLIFE600436ALNYDRREDDYASND6-month return →1-month return →
Up and to the right = strong over both horizons. Ascendis Pharma A/S is the large dot.

Fundamentals: revenue growth against valuation

0%+100%+200%0×500×1,000×ORNAV64464507EXELJAZZ6990TORNTPHARMLAURUSLABS600436SIGASNDRevenue growth (TTM) →Forward P/E →
Further right = faster growth; higher = more expensive. The dashed lines are the peer medians. Ascendis Pharma A/S is the large dot.

Capital: growth delivered against growth the price implies

0%+50%+100%+150%0%50%100%150%ORNAV64464507IPN6990TORNTPHARM1801LAURUSLABSREC600436ALNYSIGASNDGrowth delivered (Del g) →Growth the price implies (Req g, 7 yrs) →
Above the diagonal = the price needs more growth than the company has been delivering; below = the price already allows for a slowdown. Ascendis Pharma A/S is the large dot.

Ascendis Pharma A/S competitors and peer comparison

Head to head with its named competitors (ASND vs NOVO-B.CO vs PFE vs IPN.PA)
CompanyMarket cap6M returnRevenue growthOp. marginForward P/EReq g
Ascendis Pharma A/S ASND$16.0B+8%+128%10%40.8×36.4%
Novo Nordisk A/S NOVO-B.CO$190B-7%+6%48%11.9×0.1%
Pfizer PFE$168B+14%+1%26%10.4×-4.3%
Ipsen IPN.PA$14.7B-4%+14%30%10.9×-7.3%
BioMarin Pharmaceutical BMRN$10.9B+4%+20%19%10.3×6.5%
BridgeBio Pharma BBIO$14.5B+10%+167%-37%n/an/a
Takeda Pharmaceutical 4502.T$66.4B+24%+6%18%42.1×3.0%

How Ascendis Pharma A/S compares with its peers

Peer set: Industry: the same industry and sector in any market, nearest in size. This is the same default set the interactive Competitor Analysis opens with.

Ascendis Pharma A/S against its 20 peers (data as of 6 Nov 2026)
MeasureASNDPeer medianRank in peer set
1-month return+15.3%+7.8%5th highest of 21
6-month return+7.6%+3.8%8th highest of 21
Distance from 52-week high-9.0%-10.7%10th highest of 21
Revenue growth (TTM)+128.4%+18.9%2nd highest of 21
Operating margin10.3%23.1%5th lowest of 21
Forward P/E40.8×25.5×6th most expensive of 20
Growth the price implies (Req g, 7 yrs)36.4%1.4%4th most demanding of 19
Growth delivered (Del g)+152.4%+12.3%highest of 19
Hurdle (Req g minus delivered)-116.1 pp-11.2 ppleast demanding of 19
ROIC minus cost of capital+1.3 pp+7.2 pp8th lowest of 21
Net debt / EBITDA-2.8×0.5×2nd least indebted of 17

Peer table

Peer set: Industry: the same industry and sector in any market, nearest in size
CompanyMarketMarket cap6M returnRevenue growthOp. marginForward P/EReq gDelivered g
Ascendis Pharma A/S ASNDUnited States$16.0B+8%+128%10%40.8×36.4%+152.4%
Orion ORNAV.HEFinland$16.1B+51%+34%38%23.5×-6.3%+11.7%
PharmaEssentia 6446.TWTaiwan$15.8B+118%+64%38%39.2×29.3%+94.8%
Sichuan Biokin Pharmaceutical 688506.SSChina$16.4B-3%+14%-43%n/an/an/a
Shionogi & 4507.TJapan$16.6B-6%+46%29%10.9×-0.7%+11.0%
Exelixis EXELUnited States$17.0B+44%+9%40%18.2×-3.7%+18.6%
Jazz Pharmaceuticals Public JAZZUnited States$15.1B+4%+13%25%8.9×-3.9%+12.5%
Ipsen IPN.PAFrance$14.7B-4%+14%30%10.9×-7.3%+7.2%
Yunnan Baiyao 000538.SZChina$14.7B+4%+5%11%18.0×-0.5%+4.7%
Swedish Orphan Biovitrum SOBI.STSweden$17.6B+13%+15%30%25.5×-1.1%+13.1%
Sichuan Kelun-Biotech Biopharmaceutical 6990.HKHong Kong$13.9B0%+44%-38%1,255.9×56.2%+33.7%
Torrent Pharmaceuticals TORNTPHARM.NSIndia$19.1B+9%+42%22%72.2×37.9%+11.3%
Innovent Biologics 1801.HKHong Kong$19.2B-5%+43%17%53.3×11.7%+26.8%
Laurus Labs LAURUSLABS.NSIndia$13.3B+94%+23%24%77.0×50.9%+7.3%
Sbp 1177.HKHong Kong$12.7B+4%+15%30%18.3×-5.4%+5.4%
Zydus Lifesciences ZYDUSLIFE.NSIndia$12.7B+27%+24%17%29.8×n/an/a
Recordati REC.MIItaly$12.3B+3%+9%30%16.7×1.9%+12.6%
Zhangzhou Pientzehuang Pharmaceutical 600436.SSChina$12.3B-5%-19%19%42.1×25.8%+6.8%
Alnylam Pharmaceuticals ALNYUnited States$20.9B-47%+56%20%22.2×0.9%+49.8%
Dr. Reddy's Laboratories DRREDDY.NSIndia$12.1B+5%-4%9%31.8×30.1%+12.1%
Sigma Healthcare SIG.AXAustralia$22.4B-1%+209%9%37.1×28.2%+26.1%

Questions

Who are Ascendis Pharma A/S's main competitors?
Named competitors: Novo Nordisk (NOVO-B.CO), Pfizer (PFE), Ipsen (IPN.PA), BioMarin Pharmaceutical (BMRN), BridgeBio Pharma (BBIO), Takeda Pharmaceutical (4502.T). The cockpit's measured peer set (industry) also includes Orion (ORNAV.HE), PharmaEssentia (6446.TW), Sichuan Biokin Pharmaceutical (688506.SS), Shionogi & (4507.T), Exelixis (EXEL), Jazz Pharmaceuticals Public (JAZZ).
Is Ascendis Pharma A/S expensive compared with its peers?
On forward p/e it trades at 40.8× against a peer median of 25.5×, 6th most expensive of 20 in its peer set. For today's price to make sense, revenue must grow about 36% a year for seven years (Req g). Recent delivered growth is +152%, so the hurdle is -116 pp: the price already allows for a slowdown.
How has Ascendis Pharma A/S stock performed?
Over six months to 6 Nov 2026 the shares returned +7.6% against +3.8% for the median peer; over one year +29.9%.

How these numbers are made. Returns are close-to-close in local currency. Revenue growth and margins are trailing twelve months. Req g is the revenue growth that today's enterprise value requires for seven years at the company's own cost of capital; Delivered g is what it actually grew; the gap is the hurdle (honest precision about ±8 points, so read the ranking more than the decimal). No fair values, price targets or analyst ratings are shown, by design. Method and validation.