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Natera, Inc.NTRACompetitor analysis, valuation and peers

United States · USD·Health Care›Biotechnology

Runs genetic testing—prenatal screening, cancer monitoring and organ-transplant rejection tests—via proprietary molecular diagnostics.

Momentum strong 79
Mkt cap
$44.8B
US dollars, full cap
Free float
94%
of shares outstanding
$/day
$750M
20-day average traded
Fwd P/E
n/m
no positive forecast
ROIC−WACC
-35.9 pp
WACC 12.6%
Hurdle
n/a
no reverse DCF
Next earnings
118 days
4 Mar 2027
Close · USD$310.67
1D-14.6%
1W-25.0%
1M-20.5%
3M-2.4%
6M+59.9%
YTD+35.6%
1Y+55.4%
ATR %7.7%
Beta1.29
52w lowhigh29.0% off high

What Natera does

Runs genetic testing—prenatal screening, cancer monitoring and organ-transplant rejection tests—via proprietary molecular diagnostics.

Earns per test: it runs samples in its own labs and bills insurers and Medicare and, for some tests, patients. How much it collects depends on coverage and reimbursement decisions as much as test volume. Prenatal screening is the older base; Signatera, a cancer-recurrence test tailored to each patient's tumour, is the growth engine.

Products and services

  • Panorama (prenatal screening)
  • Signatera (cancer minimal residual disease)
  • Prospera (organ transplant rejection)

Customers

  • OB-GYNs and expecting parents
  • Oncologists
  • Transplant physicians

Where it sits in the supply chain

  • Healthcare
  • Diagnostics/genetic testing
  • Molecular diagnostic testing services

What could go right

  • Signatera oncology test adoption and payer coverage
  • Volume growth across all test lines

What could go wrong

  • Reimbursement/payer coverage risk
  • Competitive pricing pressure in liquid biopsy

Moat: narrow (IP / patents, data, process know-how). Proprietary personalized-assay technology (Signatera) and a large clinical-evidence base create switching costs.

Headquarters: Austin, Texas, US · Founded: 2004 · Employees: 6,140

Named competitors

Natera at a glance

Size Natera (NTRA) is a United States Health Care company (Biotechnology) with a market value of $44.8B, the 280th largest of 3,117 United States companies the cockpit tracks. Shares closed at $310.67 on 6 Nov 2026.

Performance Over six months the shares gained 59.9%, against +18.5% for the median peer and -1.1% for the United States market (cap-weighted) — 4th highest of 20 in its peer set.

Growth Revenue grew 37.8% over the last twelve months (peer median +13.2%); the operating margin is -10.6% (peer median 25.1%).

Valuation It trades at 16.2× enterprise value to sales against a peer median of 8.0× (5th most expensive of 19).

Capital Return on invested capital runs 35.9 points below its cost of capital (12.6% WACC).

Short interest Short interest is 4.1% of the free float (15 Oct 2026).

Next results Next results expected around 4 Mar 2027 (exchange calendar; dates can move).

Relative performance

10015020011 May 202611 Aug 20266 Nov 2026NTRA 156Peer median 119
Six months, rebased to 100: Natera against the median of its 19 peers (local-currency closes).

Natera financials

Reported figures in USD; fiscal year ends 2025-12-31. TTM = trailing twelve months.
TTMFY2025FY2024FY2023FY2022
Revenue$2.71B$2.31B$1.70B$1.08B$820M
Revenue growth—+36%+57%+32%—
Gross profit$1.75B$1.49B$1.02B$493M$364M
EBITDA-$220M-$263M-$191M-$405M-$501M
Net income-$192M-$208M-$190M-$435M-$548M
Free cash flow$84.2M$109M$69.2M-$286M-$479M
Capital expenditure$177M$139M$76.9M$39.2M$47.7M
Total debt$238M$214M$187M$442M$446M

Quarterly statements and history in the cockpit →

Natera competitor charts

The default views of Competitor Analysis ▸ Charts, drawn from the same data. Open them in the cockpit to change the axes, pin companies and read every value.

Performance: 6-month against 1-month return

0%+50%+100%-25%0%+25%+50%IQV207940LONNARGX068270GMABCSL2269UTHRBNTXMRNASMMT1093HALOTECHKYMRNTRA6-month return →1-month return →
Up and to the right = strong over both horizons. Natera is the large dot.

Fundamentals: revenue growth against valuation

0%+50%+100%+150%0×50×100×IQV207940LONNARGX068270GMABCSL2269MRNANBIXBBIO1093KYMRNTRARevenue growth (TTM) →EV / Sales →
Further right = faster growth; higher = more expensive. The dashed lines are the peer medians. Natera is the large dot.

Natera competitors and peer comparison

Head to head with its named competitors (NTRA vs ILMN vs GH vs MYGN)
CompanyMarket cap6M returnRevenue growthOp. marginEV / SalesReq g
Natera NTRA$44.8B+60%+38%-11%16.2×n/a
Illumina ILMN$32.2B+50%+6%21%7.3×27.1%
Guardant Health GH$20.2B+58%+43%-40%17.7×n/a
Myriad Genetics MYGN$566M+38%-3%-11%0.8×n/a

How Natera compares with its peers

Peer set: Industry: the same industry and sector in any market, nearest in size. This is the same default set the interactive Competitor Analysis opens with.

Natera against its 19 peers (data as of 6 Nov 2026)
MeasureNTRAPeer medianRank in peer set
1-month return-20.5%+11.3%lowest of 20
6-month return+59.9%+18.5%4th highest of 20
Distance from 52-week high-29.0%-11.7%3rd lowest of 20
Revenue growth (TTM)+37.8%+13.2%7th highest of 19
Operating margin-10.6%25.1%5th lowest of 19
EV / Sales16.2×8.0×5th most expensive of 19
ROIC minus cost of capital-35.9 pp+2.8 pp3rd lowest of 19

Peer table

Peer set: Industry: the same industry and sector in any market, nearest in size
CompanyMarketMarket cap6M returnRevenue growthOp. marginEV / SalesReq gDelivered g
Natera NTRAUnited States$44.8B+60%+38%-11%16.2×n/an/a
Iqvia IQVUnited States$44.8B+52%+9%14%3.4×17.3%+7.5%
Samsung Biologics 207940.KSSouth Korea$53.7B+3%-20%43%16.7×9.6%+31.4%
Lonza LONN.SWSwitzerland$55.4B+39%-11%25%7.7×15.0%+7.7%
argenx SE Sponsored ADR ARGXUnited States$57.5B+19%+71%29%10.0×10.9%+151.4%
Celltrion 068270.KSSouth Korea$34.3B+10%+40%32%8.6×8.3%+17.6%
Genmab A/S GMAB.CODenmark$32.1B+115%+14%32%9.0×11.6%+19.5%
CSL CSL.AXAustralia$67.2B+105%-2%26%4.9×7.1%+11.0%
Wuxi Bio 2269.HKHong Kong$25.0B+43%+22%32%7.3×21.8%+30.2%
United Therapeutics UTHRUnited States$24.1B-1%+2%44%6.9×-0.4%+16.5%
BioNTech SE Sponsored ADR BNTXUnited States$22.8B-7%-1%-38%2.0×5.7%+42.6%
Moderna MRNAUnited States$101B+43%-28%-149%43.8×n/an/a
Neurocrine Biosciences NBIXUnited States$16.7B+8%+38%25%4.4×-1.7%+22.3%
BridgeBio Pharma BBIOUnited States$14.5B+10%+167%-37%18.3×n/an/a
Summit Therapeutics SMMTUnited States$13.1B-10%n/an/an/an/an/a
Elanco Animal Health ELANUnited States$12.9B+9%+12%7%3.2×34.8%+7.6%
Cspc Pharma 1093.HKHong Kong$12.4B+5%+25%28%2.2×-10.3%+0.1%
Halozyme Therapeutics HALOUnited States$11.8B+62%+41%57%8.2×2.5%+39.2%
Bio-Techne TECHUnited States$11.4B+51%0%22%9.4×31.3%+5.5%
Kymera Therapeutics KYMRUnited States$11.2B+53%+134%-396%101.2×n/an/a

Questions

Who are Natera's main competitors?
Named competitors: Illumina (GRAIL) (ILMN), Guardant Health (GH), Exact Sciences (private or unlisted), Myriad Genetics (MYGN). The cockpit's measured peer set (industry) also includes Iqvia (IQV), Samsung Biologics (207940.KS), Lonza (LONN.SW), argenx SE Sponsored ADR (ARGX), Celltrion (068270.KS), Genmab A/S (GMAB.CO).
Is Natera expensive compared with its peers?
On ev / sales it trades at 16.2× against a peer median of 8.0×, 5th most expensive of 19 in its peer set.
How has Natera stock performed?
Over six months to 6 Nov 2026 the shares returned +59.9% against +18.5% for the median peer; over one year +55.4%.

How these numbers are made. Returns are close-to-close in local currency. Revenue growth and margins are trailing twelve months. Req g is the revenue growth that today's enterprise value requires for seven years at the company's own cost of capital; Delivered g is what it actually grew; the gap is the hurdle (honest precision about ±8 points, so read the ranking more than the decimal). No fair values, price targets or analyst ratings are shown, by design. Method and validation.