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Illumina, Inc.ILMNCompetitor analysis, valuation and peers

United States · USD·Health Care›Medical Specialties

World's leading maker of DNA sequencing systems and consumables used in genomics research, clinical diagnostics and agrigenomics.

Momentum leader 83
Mkt cap
$32.2B
US dollars, full cap
Free float
100%
of shares outstanding
$/day
$604M
20-day average traded
Fwd P/E
35.7×
forward earnings
ROIC−WACC
+6.3 pp
WACC 11.8%
Hurdle
+21 pp
Req g minus delivered
Official | Implied
BBB / BBB
agencies · bond market
Next earnings
97 days
11 Feb 2027
Close · USD$213.13
1D+2.5%
1W-9.7%
1M-19.4%
3M+11.1%
6M+50.2%
YTD+62.5%
1Y+74.1%
ATR %7.8%
Beta1.01
52w lowhigh31.1% off high

What Illumina does

World's leading maker of DNA sequencing systems and consumables used in genomics research, clinical diagnostics and agrigenomics.

Sells sequencers once, then earns most revenue from the chemicals and flow cells used on every run, so the installed machine count matters. It spun off Grail, the cancer-screening firm it bought in 2021, in 2024 after antitrust challenges, and in 2025 China restricted its imports into the country.

Products and services

  • Sequencing systems (NovaSeq, MiSeq)
  • Sequencing consumables/reagents
  • Clinical genomics/oncology via partners

Customers

  • Genomics research labs
  • Clinical diagnostic labs
  • Pharma/biotech companies
  • Agrigenomics companies

Where it sits in the supply chain

  • Healthcare/Life Sciences
  • Genomics tools
  • Next-generation DNA sequencing

What could go right

  • Whole-genome sequencing cost decline driving adoption
  • Clinical/oncology sequencing volume growth

What could go wrong

  • Rising sequencing-platform competition (MGI, ONT)
  • China market/geopolitical exposure

Moat: wide (scale, installed base, switching costs). Dominant installed sequencer base and patent estate give pricing power in the sequencing-consumables model.

Headquarters: San Diego, California, USA · Founded: 1998 · Employees: 8,600

Named competitors

Illumina at a glance

Size Illumina (ILMN) is a United States Health Care company (Medical Specialties) with a market value of $32.2B, the 342nd largest of 3,117 United States companies the cockpit tracks. Shares closed at $213.13 on 6 Nov 2026.

Performance Over six months the shares gained 50.2%, against +26.9% for the median peer and -1.1% for the United States market (cap-weighted) — 5th highest of 21 in its peer set.

Growth Revenue grew 6.0% over the last twelve months (peer median +8.5%); the operating margin is 20.7% (peer median 20.1%).

Valuation It trades at 35.7× forward earnings against a peer median of 26.7× (5th most expensive of 20).

Price implies For today's price to make sense, revenue must grow about 27% a year for seven years (Req g). Recent delivered growth is +6%, so the hurdle is +21 pp: the price needs faster growth than the company has been delivering — of companies that just grew 25–50% a year, 93.8% slowed down over the next four years.

Capital Return on invested capital runs 6.3 points above its cost of capital (11.8% WACC).

Backlog Backlog (remaining performance obligations) was $933M at 27 Sep 2026, up 25% on a year earlier — 0.2 years of trailing revenue. Backlog detail →

Credit Illumina has 4 bonds outstanding ($1.80B), rated BBB by the agencies and trading like BBB at a weighted spread of 83 bp.

Short interest Short interest is 5.2% of the free float (15 Oct 2026).

Next results Next results expected around 11 Feb 2027 (exchange calendar; dates can move).

Relative performance

10015020011 May 202611 Aug 20266 Nov 2026ILMN 150Peer median 129
Six months, rebased to 100: Illumina against the median of its 20 peers (local-currency closes).

Illumina financials

Reported figures in USD; fiscal year ends 2025-12-31. TTM = trailing twelve months.
TTMFY2025FY2024FY2023FY2022
Revenue$4.54B$4.34B$4.36B$4.50B$4.58B
Revenue growth—0%-3%-2%—
Gross profit$3.10B$2.89B$2.85B$2.75B$2.97B
EBITDA$1.22B$1.13B$739M$338M$748M
Net income$895M$850M-$1.22B-$1.16B-$4.40B
Free cash flow$1.06B$931M$709M$282M$106M
Capital expenditure$593M$158M$209M$196M$466M
Total debt$2.31B$2.55B$2.62B$2.26B$3.56B

Quarterly statements and history in the cockpit →

Illumina competitor charts

The default views of Competitor Analysis ▸ Charts, drawn from the same data. Open them in the cockpit to change the axes, pin companies and read every value.

Performance: 6-month against 1-month return

0%+20%+40%+60%0%+20%RMD300760MTDDXCMGEHCWSTALCDIMSTE4543WAT7741ASTMNSOONGHZBHSRTMDLNIDXXILMN6-month return →1-month return →
Up and to the right = strong over both horizons. Illumina is the large dot.

Fundamentals: revenue growth against valuation

0%+25%+50%+75%10×20×30×40×RMD300760MTDDXCMGEHCWSTALCDIMSTEWATSTMNSOONZBHSRTILMNRevenue growth (TTM) →Forward P/E →
Further right = faster growth; higher = more expensive. The dashed lines are the peer medians. Illumina is the large dot.

Capital: growth delivered against growth the price implies

0%+20%+40%0%20%40%RMD300760MTDDXCMGEHCWSTALCDIMSTE4543WATASTMNSOONZBHMDLNIDXXILMNGrowth delivered (Del g) →Growth the price implies (Req g, 7 yrs) →
Above the diagonal = the price needs more growth than the company has been delivering; below = the price already allows for a slowdown. Illumina is the large dot.

Illumina competitors and peer comparison

Head to head with its named competitors (ILMN vs TMO vs 688114.SS vs PACB)
CompanyMarket cap6M returnRevenue growthOp. marginForward P/EReq g
Illumina ILMN$32.2B+50%+6%21%35.7×27.1%
Thermo Fisher Scientific TMO$257B+50%+8%19%25.8×20.9%
MGI Tech 688114.SS$3.42B+9%+2%-7%n/a46.5%
Pacific Biosciences of California PACB$701M+60%+2%-102%n/an/a
Oxford Nanopore Technologies ONT.L$2.71B+75%+15%-55%n/an/a

How Illumina compares with its peers

Peer set: Industry: the same industry and sector in any market, nearest in size. This is the same default set the interactive Competitor Analysis opens with.

Illumina against its 20 peers (data as of 6 Nov 2026)
MeasureILMNPeer medianRank in peer set
1-month return-19.4%+11.8%lowest of 21
6-month return+50.2%+26.9%5th highest of 21
Distance from 52-week high-31.1%-7.6%lowest of 21
Revenue growth (TTM)+6.0%+8.5%7th lowest of 21
Operating margin20.7%20.1%10th highest of 21
Forward P/E35.7×26.7×5th most expensive of 20
Growth the price implies (Req g, 7 yrs)27.1%15.2%4th most demanding of 20
Growth delivered (Del g)+6.0%+9.2%6th lowest of 20
Hurdle (Req g minus delivered)+21.1 pp+2.4 pp3rd most demanding of 20
ROIC minus cost of capital+6.3 pp+4.1 pp10th highest of 21
EV / EBITDA27.2×20.2×5th most expensive of 19
Net debt / EBITDA0.8×1.0×8th least indebted of 19
Bond spread83 bp77 bp4th widest of 8

Peer table

Peer set: Industry: the same industry and sector in any market, nearest in size
CompanyMarketMarket cap6M returnRevenue growthOp. marginForward P/EReq gDelivered g
Illumina ILMNUnited States$32.2B+50%+6%21%35.7×27.1%+6.0%
ResMed RMDUnited States$33.1B+14%+9%34%19.1×4.9%+12.1%
Shenzhen Mindray Bio-Medical Electronics 300760.SZChina$33.4B+9%+5%28%27.1×0.9%+9.7%
Mettler Toledo MTDUnited States$34.5B+53%+7%28%33.9×20.3%+5.5%
Dexcom DXCMUnited States$29.6B+31%+13%24%27.0×18.5%+19.3%
GE HealthCare GEHCUnited States$37.2B+30%+7%14%15.4×4.3%+3.7%
West Pharmaceutical Services WSTUnited States$27.9B+23%+13%23%39.8×25.2%+7.5%
Alcon ALC.SWSwitzerland$37.5B+22%-1%11%21.4×12.9%+6.1%
Sartorius Stedim Biotech DIM.PAFrance$24.7B+38%+4%19%45.5×33.1%+9.2%
Steris STEUnited States$24.6B+22%+8%20%21.4×13.7%+13.8%
Terumo 4543.TJapan$23.4B+25%+14%17%24.6×8.7%+13.0%
Waters WATUnited States$45.0B+29%+81%10%28.6×46.2%+6.0%
Hoya 7741.TJapan$47.4B-23%+13%31%26.7×13.3%+11.6%
Agilent Technologies AUnited States$49.3B+51%+9%24%26.6×22.6%+5.4%
Straumann STMN.SWSwitzerland$20.4B+25%+2%21%31.9×15.2%+12.8%
Sonova SOON.SWSwitzerland$20.3B+62%-7%21%25.6×7.1%+6.7%
Guardant Health GHUnited States$20.2B+58%+43%-40%n/an/an/a
Zimmer Biomet ZBHUnited States$20.1B+29%+7%16%12.0×-1.4%+3.2%
Sartorius SRT.DEGermany$20.0B+34%+4%18%42.6×24.9%+8.7%
Medline MDLNUnited States$52.1B0%+12%6%26.1×17.1%+9.9%
Idexx Laboratories IDXXUnited States$53.3B+21%+12%32%41.5×28.0%+9.7%

Illumina bonds and credit

Illumina has 4 bonds outstanding with $1.80B face value. The agencies rate it BBB; its bonds trade like BBB. Weighted yield 5.33%, a spread of 83 bp over government bonds.

Every bond, yield and spread in the cockpit →

Illumina backlog

Illumina reported $933M of remaining performance obligations at 27 Sep 2026, up 25% from a year earlier and down 7% from the previous quarter. That is 0.2 years of trailing revenue already under contract. Book-to-bill last quarter: 0.94.

Questions

Who are Illumina's main competitors?
Named competitors: Thermo Fisher Scientific (Ion Torrent) (TMO), MGI Tech (688114.SS), Pacific Biosciences (PACB), Oxford Nanopore Technologies (ONT.L). The cockpit's measured peer set (industry) also includes ResMed (RMD), Shenzhen Mindray Bio-Medical Electronics (300760.SZ), Mettler Toledo (MTD), Dexcom (DXCM), GE HealthCare (GEHC), West Pharmaceutical Services (WST).
Is Illumina expensive compared with its peers?
On forward p/e it trades at 35.7× against a peer median of 26.7×, 5th most expensive of 20 in its peer set. For today's price to make sense, revenue must grow about 27% a year for seven years (Req g). Recent delivered growth is +6%, so the hurdle is +21 pp: the price needs faster growth than the company has been delivering — of companies that just grew 25–50% a year, 93.8% slowed down over the next four years.
How has Illumina stock performed?
Over six months to 6 Nov 2026 the shares returned +50.2% against +26.9% for the median peer; over one year +74.1%.
What is Illumina's backlog?
Illumina's remaining performance obligations (contracted revenue not yet recognised) were $933M at 27 Sep 2026, +25% on a year earlier.

How these numbers are made. Returns are close-to-close in local currency. Revenue growth and margins are trailing twelve months. Req g is the revenue growth that today's enterprise value requires for seven years at the company's own cost of capital; Delivered g is what it actually grew; the gap is the hurdle (honest precision about ±8 points, so read the ranking more than the decimal). No fair values, price targets or analyst ratings are shown, by design. Method and validation.