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BioNTech SE Sponsored ADRBNTXCompetitor analysis, valuation and peers

United States · USD·Health Care›Biotechnology

German mRNA biotech that co-developed the Pfizer-BioNTech COVID vaccine, now focused on mRNA and antibody cancer therapies.

Momentum neutral 42
Mkt cap
$22.8B
US dollars, full cap
Free float
100%
of shares outstanding
$/day
$101M
20-day average traded
Fwd P/E
n/m
no positive forecast
ROIC−WACC
-35.5 pp
WACC 11.2%
Hurdle
-37 pp
Req g minus delivered
Next earnings
116 days
2 Mar 2027
Close · USD$87.51
1D+1.9%
1W-0.8%
1M-4.9%
3M-5.7%
6M-7.0%
YTD-8.1%
1Y-15.4%
ATR %3.6%
Beta1.05
52w lowhigh29.4% off high

What BioNTech SE Sponsored ADR does

German mRNA biotech that co-developed the Pfizer-BioNTech COVID vaccine, now focused on mRNA and antibody cancer therapies.

Most revenue still comes from the COVID-19 vaccine Comirnaty, which Pfizer sells in most markets and the two share the profit on, while BioNTech sells it itself in Germany and Turkey. Its cancer drugs are not yet approved, and in 2025 it agreed to co-develop an antibody cancer drug with Bristol Myers Squibb.

Products and services

  • Comirnaty (COVID-19 vaccine, with Pfizer)
  • Oncology pipeline (individualized mRNA cancer vaccines)
  • Antibody-drug conjugates (partnered programs)

Customers

  • Governments/public health systems (vaccine)
  • Oncologists (pipeline, future)

Where it sits in the supply chain

  • Healthcare
  • Biotechnology
  • mRNA and immunotherapy drug discovery…

What could go right

  • Oncology pipeline data readouts
  • Diversification beyond COVID vaccine revenue

What could go wrong

  • Steep COVID vaccine revenue decline
  • Binary clinical trial risk in oncology pipeline

Moat: narrow (IP / patents, process know-how). Pioneering mRNA platform IP and manufacturing scale, though pipeline value remains largely unproven outside COVID.

Headquarters: Mainz, Germany · Founded: 2008 · Employees: 7,807

Named competitors

BioNTech SE Sponsored ADR at a glance

Size BioNTech SE Sponsored ADR (BNTX) is a United States Health Care company (Biotechnology) with a market value of $22.8B, the 455th largest of 3,117 United States companies the cockpit tracks. Shares closed at $87.51 on 6 Nov 2026.

Performance Over six months the shares fell 7.0%, against +15.5% for the median peer and -1.1% for the United States market (cap-weighted) — 3rd lowest of 21 in its peer set.

Growth Revenue fell 1.1% over the last twelve months (peer median +20.8%); the operating margin is -37.6% (peer median 24.6%).

Valuation It trades at 2.0× enterprise value to sales against a peer median of 8.0× (cheapest of 19).

Price implies For today's price to make sense, revenue must grow about 6% a year for seven years (Req g). Recent delivered growth is +43%, so the hurdle is -37 pp: the price already allows for a slowdown.

Capital Return on invested capital runs 35.5 points below its cost of capital (11.2% WACC).

Short interest Short interest is 0.9% of the free float (15 Oct 2026).

Next results Next results expected around 2 Mar 2027 (exchange calendar; dates can move).

Relative performance

10012011 May 202611 Aug 20266 Nov 2026Peer median 118BNTX 94
Six months, rebased to 100: BioNTech SE Sponsored ADR against the median of its 20 peers (local-currency closes).

BioNTech SE Sponsored ADR financials

Reported figures in USD; fiscal year ends 2025-12-31. TTM = trailing twelve months.
TTMFY2025FY2024FY2023FY2022
Revenue$3.09B$3.24B$2.98B$4.13B$18.2B
Revenue growth—+9%-28%-77%—
Gross profit$1.97B$2.51B$2.39B$3.51B$18.0B
EBITDA-$373M-$301M-$374M$1.18B$16.1B
Net income-$1.97B-$1.28B-$720M$1.01B$9.92B
Free cash flow$480M$317M-$265M$5.54B$13.9B
Capital expenditure$301M$845M$489M$763M$382M
Total debt$361M$314M$263M$242M$226M

Quarterly statements and history in the cockpit →

BioNTech SE Sponsored ADR competitor charts

The default views of Competitor Analysis ▸ Charts, drawn from the same data. Open them in the cockpit to change the axes, pin companies and read every value.

Performance: 6-month against 1-month return

0%+20%+40%+60%-20%0%+20%UTHR2269NBIXGMAB068270BBIOSMMT1093HALONTRAIQVTECHKYMRBMRN002422196170PCVX207940LONNBNTX6-month return →1-month return →
Up and to the right = strong over both horizons. BioNTech SE Sponsored ADR is the large dot.

Fundamentals: revenue growth against valuation

0%+50%+100%+150%0×50×100×UTHR2269NBIXGMAB068270BBIOELANNTRAKYMR196170207940LONNBNTXRevenue growth (TTM) →EV / Sales →
Further right = faster growth; higher = more expensive. The dashed lines are the peer medians. BioNTech SE Sponsored ADR is the large dot.

Capital: growth delivered against growth the price implies

0%+20%+40%0%20%40%UTHR2269NBIXGMAB068270ELAN1093HALOIQVTECHBMRN002422196170207940LONNBNTXGrowth delivered (Del g) →Growth the price implies (Req g, 7 yrs) →
Above the diagonal = the price needs more growth than the company has been delivering; below = the price already allows for a slowdown. BioNTech SE Sponsored ADR is the large dot.

BioNTech SE Sponsored ADR competitors and peer comparison

Head to head with its named competitors (BNTX vs MRNA vs PFE vs RO.SW)
CompanyMarket cap6M returnRevenue growthOp. marginEV / SalesReq g
BioNTech SE Sponsored ADR BNTX$22.8B-7%-1%-38%2.0×5.7%
Moderna MRNA$101B+43%-28%-149%43.8×n/a
Pfizer PFE$168B+14%+1%26%3.4×-4.3%
Roche RO.SW$385B+22%-1%31%5.6×0.9%

How BioNTech SE Sponsored ADR compares with its peers

Peer set: Industry: the same industry and sector in any market, nearest in size. This is the same default set the interactive Competitor Analysis opens with.

BioNTech SE Sponsored ADR against its 20 peers (data as of 6 Nov 2026)
MeasureBNTXPeer medianRank in peer set
1-month return-4.9%+5.2%6th lowest of 21
6-month return-7.0%+15.5%3rd lowest of 21
Distance from 52-week high-29.4%-16.2%4th lowest of 21
Revenue growth (TTM)-1.1%+20.8%3rd lowest of 19
Operating margin-37.6%24.6%2nd lowest of 19
EV / Sales2.0×8.0×cheapest of 19
Growth the price implies (Req g, 7 yrs)5.7%9.6%5th least demanding of 16
Growth delivered (Del g)+42.6%+16.5%highest of 16
Hurdle (Req g minus delivered)-36.9 pp-8.4 ppleast demanding of 16
ROIC minus cost of capital-35.5 pp+1.6 pp4th lowest of 20

Peer table

Peer set: Industry: the same industry and sector in any market, nearest in size
CompanyMarketMarket cap6M returnRevenue growthOp. marginEV / SalesReq gDelivered g
BioNTech SE Sponsored ADR BNTXUnited States$22.8B-7%-1%-38%2.0×5.7%+42.6%
United Therapeutics UTHRUnited States$24.1B-1%+2%44%6.9×-0.4%+16.5%
Wuxi Bio 2269.HKHong Kong$25.0B+43%+22%32%7.3×21.8%+30.2%
Neurocrine Biosciences NBIXUnited States$16.7B+8%+38%25%4.4×-1.7%+22.3%
Genmab A/S GMAB.CODenmark$32.1B+115%+14%32%9.0×11.6%+19.5%
Celltrion 068270.KSSouth Korea$34.3B+10%+40%32%8.6×8.3%+17.6%
BridgeBio Pharma BBIOUnited States$14.5B+10%+167%-37%18.3×n/an/a
Summit Therapeutics SMMTUnited States$13.1B-10%n/an/an/an/an/a
Elanco Animal Health ELANUnited States$12.9B+9%+12%7%3.2×34.8%+7.6%
Cspc Pharma 1093.HKHong Kong$12.4B+5%+25%28%2.2×-10.3%+0.1%
Halozyme Therapeutics HALOUnited States$11.8B+62%+41%57%8.2×2.5%+39.2%
Natera NTRAUnited States$44.8B+60%+38%-11%16.2×n/an/a
Iqvia IQVUnited States$44.8B+52%+9%14%3.4×17.3%+7.5%
Bio-Techne TECHUnited States$11.4B+51%0%22%9.4×31.3%+5.5%
Kymera Therapeutics KYMRUnited States$11.2B+53%+134%-396%101.2×n/an/a
BioMarin Pharmaceutical BMRNUnited States$10.9B+4%+20%19%3.9×6.5%+12.0%
Sichuan Kelun Pharmaceutical 002422.SZChina$10.8B+30%0%9%3.9×7.2%+2.3%
ALTEOGEN 196170.KSSouth Korea$10.3B-46%+61%53%43.0×29.8%+38.5%
Vaxcyte PCVXUnited States$10.1B+21%n/an/an/an/an/a
Samsung Biologics 207940.KSSouth Korea$53.7B+3%-20%43%16.7×9.6%+31.4%
Lonza LONN.SWSwitzerland$55.4B+39%-11%25%7.7×15.0%+7.7%

Questions

Who are BioNTech SE Sponsored ADR's main competitors?
Named competitors: Moderna (MRNA), Pfizer (PFE), Roche (RO.SW). The cockpit's measured peer set (industry) also includes United Therapeutics (UTHR), Wuxi Bio (2269.HK), Neurocrine Biosciences (NBIX), Genmab A/S (GMAB.CO), Celltrion (068270.KS), BridgeBio Pharma (BBIO).
Is BioNTech SE Sponsored ADR expensive compared with its peers?
On ev / sales it trades at 2.0× against a peer median of 8.0×, cheapest of 19 in its peer set. For today's price to make sense, revenue must grow about 6% a year for seven years (Req g). Recent delivered growth is +43%, so the hurdle is -37 pp: the price already allows for a slowdown.
How has BioNTech SE Sponsored ADR stock performed?
Over six months to 6 Nov 2026 the shares returned -7.0% against +15.5% for the median peer; over one year -15.4%.

How these numbers are made. Returns are close-to-close in local currency. Revenue growth and margins are trailing twelve months. Req g is the revenue growth that today's enterprise value requires for seven years at the company's own cost of capital; Delivered g is what it actually grew; the gap is the hurdle (honest precision about ±8 points, so read the ranking more than the decimal). No fair values, price targets or analyst ratings are shown, by design. Method and validation.