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← CockpitCompetitor Analysis › COGT Cogent Biosciences, Inc.Open in the cockpit ↗

Cogent Biosciences, Inc.COGTCompetitor analysis, valuation and peers

United States · USD·Health Care›Biotechnology

Biotech developing bezuclastinib, a precision KIT-inhibitor drug for systemic mastocytosis and gastrointestinal stromal tumors.

Momentum weak 33
Mkt cap
$5.49B
US dollars, full cap
Free float
90%
of shares outstanding
$/day
$65.4M
20-day average traded
Fwd P/E
n/m
no positive forecast
ROIC−WACC
n/a
WACC 6.6%
Hurdle
n/a
no reverse DCF
Next earnings
4 days
10 Nov 2026
Close · USD$31.64
1D+7.0%
1W+2.0%
1M+5.2%
3M-23.8%
6M-8.9%
YTD-10.9%
1Y+119.5%
ATR %4.9%
Beta2.29
52w lowhigh27.6% off high

What Cogent Biosciences does

Biotech developing bezuclastinib, a precision KIT-inhibitor drug for systemic mastocytosis and gastrointestinal stromal tumors.

Has no product to sell yet, so spending is funded by investors' money rather than customers. Everything rests on one drug, bezuclastinib, in trials for a rare blood-cell disorder, systemic mastocytosis, and for gastrointestinal stromal tumors, and on the regulatory decisions that follow.

Products and services

  • Bezuclastinib (systemic mastocytosis, GIST, pipeline)

Customers

  • Hematologists/oncologists treating mastocytosis an

Where it sits in the supply chain

  • Healthcare
  • Biotechnology
  • Precision oncology/rare disease drug…

What could go right

  • Approval and launch in mastocytosis/GIST niches
  • Differentiated efficacy/safety versus Blueprint's Ayvakit

What could go wrong

  • Pre-revenue, binary late-stage trial risk
  • An established competitor already on market

Moat: narrow (IP / patents). A selective KIT D816V inhibitor with a differentiated safety profile versus approved competitors in a niche rare-disease market.

Headquarters: Cambridge, Massachusetts, US · Founded: 2016 · Employees: 258

Named competitors

Cogent Biosciences at a glance

Size Cogent Biosciences (COGT) is a United States Health Care company (Biotechnology) with a market value of $5.49B, the 1119th largest of 3,117 United States companies the cockpit tracks. Shares closed at $31.64 on 6 Nov 2026.

Performance Over six months the shares fell 8.9%, against +2.4% for the median peer and -1.1% for the United States market (cap-weighted) — 6th lowest of 21 in its peer set.

Credit Cogent Biosciences has 1 bond outstanding ($230M).

Short interest Short interest is 11.3% of the free float (15 Oct 2026).

Next results Next results expected around 10 Nov 2026 (exchange calendar; dates can move).

Relative performance

8010012011 May 202611 Aug 20266 Nov 2026Peer median 102COGT 93
Six months, rebased to 100: Cogent Biosciences against the median of its 20 peers (local-currency closes).

Cogent Biosciences financials

Reported figures in USD; fiscal year ends 2025-12-31. TTM = trailing twelve months.
TTMFY2025FY2024FY2023FY2022
Revenue$0$0$0$0$0
Revenue growth—————
Gross profit-$4.85M-$4.62M-$4.40M-$3.59M-$5.88M
EBITDA-$384M-$329M-$272M-$205M-$142M
Net income-$377M-$329M-$256M-$192M-$140M
Free cash flow-$309M-$266M-$208M-$156M-$126M
Capital expenditure$1.70M$1.55M$573,000$2.80M$6.86M
Total debt$244M$239M$17.5M$18.9M$19.6M

Quarterly statements and history in the cockpit →

Cogent Biosciences competitor charts

The default views of Competitor Analysis ▸ Charts, drawn from the same data. Open them in the cockpit to change the axes, pin companies and read every value.

Performance: 6-month against 1-month return

-50%0%+50%+100%+150%-20%0%ANTHEM300347300122SRRK1530EWTX002252CRSPKODDNTH603392603127000661CGONADPTAXSMCAIRLAYTXGCOGT6-month return →1-month return →
Up and to the right = strong over both horizons. Cogent Biosciences is the large dot.

Cogent Biosciences competitors and peer comparison

Head to head with its named competitors (COGT vs NOVN.SW vs SAN.PA vs 4528.T)
CompanyMarket cap6M returnRevenue growthOp. marginEV / SalesReq g
Cogent Biosciences COGT$5.49B-9%n/an/an/an/a
Novartis NOVN.SW$298B+15%-4%30%6.3×1.7%
Sanofi SAN.PA$113B+14%+15%27%2.6×-5.4%
ONO Pharmaceutical 4528.T$7.01B+2%-2%22%2.0×-8.2%

How Cogent Biosciences compares with its peers

Peer set: Industry: the same industry and sector in any market, nearest in size. This is the same default set the interactive Competitor Analysis opens with.

Cogent Biosciences against its 20 peers (data as of 6 Nov 2026)
MeasureCOGTPeer medianRank in peer set
1-month return+5.2%+2.0%9th highest of 21
6-month return-8.9%+2.4%6th lowest of 21
Distance from 52-week high-27.6%-25.5%10th lowest of 21

Peer table

Peer set: Industry: the same industry and sector in any market, nearest in size
CompanyMarketMarket cap6M returnRevenue growthOp. marginEV / SalesReq gDelivered g
Cogent Biosciences COGTUnited States$5.49B-9%n/an/an/an/an/a
Anthem Biosciences ANTHEM.NSIndia$5.46B+17%-1%35%24.9×36.7%+26.2%
Hangzhou Tigermed Consulting 300347.SZChina$5.58B-6%+16%10%5.4×28.4%+16.4%
Chongqing Zhifei Biological Products 300122.SZChina$5.35B-2%-28%-210%5.4×-6.4%-10.0%
Scholar Rock SRRKUnited States$5.72B-3%n/an/an/an/an/a
3SBio 1530.HKHong Kong$4.92B-34%+102%61%1.2×n/an/a
Edgewise Therapeutics EWTXUnited States$4.89B+28%n/an/an/an/an/a
Shanghai RAAS Blood Products 002252.SZChina$4.89B-11%-22%17%5.7×n/an/a
CRISPR Therapeutics CRSPUnited States$4.86B-9%-34%-2,059%133.6×n/an/a
Kodiak Sciences KODUnited States$6.24B+142%n/an/an/an/an/a
Dianthus Therapeutics DNTHUnited States$4.81B-1%-61%-11,441%2,087.9×n/an/a
Immunovant IMVTUnited States$6.31B+5%n/an/an/an/an/a
Beijing Wantai Biological Pharmacy Enterprise 603392.SSChina$4.72B-37%+8%-35%14.5×n/an/a
Joinn Laboratories (China) 603127.SSChina$4.58B+15%+12%-4%15.1×n/an/a
Changchun High-Tech Industry (Group) 000661.SZChina$4.51B-13%-18%-1%2.8×32.2%+7.1%
CG Oncology CGONUnited States$6.74B+9%+1,030%-4,056%917.8×n/an/a
Adaptive Biotechnologies ADPTUnited States$4.47B+103%+50%-12%14.7×n/an/a
Axsome Therapeutics AXSMUnited States$6.96B-39%+54%-19%7.9×n/an/a
Caris Life Sciences CAIUnited States$7.13B+56%+85%15%6.9×18.7%+85.4%
Relay Therapeutics RLAYUnited States$4.08B+46%+24%-2,999%308.8×n/an/a
10x Genomics TXGUnited States$7.72B+174%-4%-14%11.8×41.8%+16.6%

Cogent Biosciences bonds and credit

Cogent Biosciences has 1 bond outstanding with $230M face value.

Every bond, yield and spread in the cockpit →

Questions

Who are Cogent Biosciences's main competitors?
Named competitors: Blueprint Medicines (Ayvakit) (private or unlisted), Novartis (Gleevec, in GIST) (NOVN.SW), Sanofi (SAN.PA), Ono Pharmaceutical (4528.T). The cockpit's measured peer set (industry) also includes Anthem Biosciences (ANTHEM.NS), Hangzhou Tigermed Consulting (300347.SZ), Chongqing Zhifei Biological Products (300122.SZ), Scholar Rock (SRRK), 3SBio (1530.HK), Edgewise Therapeutics (EWTX).
How has Cogent Biosciences stock performed?
Over six months to 6 Nov 2026 the shares returned -8.9% against +2.4% for the median peer; over one year +119.5%.

How these numbers are made. Returns are close-to-close in local currency. Revenue growth and margins are trailing twelve months. Req g is the revenue growth that today's enterprise value requires for seven years at the company's own cost of capital; Delivered g is what it actually grew; the gap is the hurdle (honest precision about ±8 points, so read the ranking more than the decimal). No fair values, price targets or analyst ratings are shown, by design. Method and validation.