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← CockpitCompetitor Analysis › EWTX Edgewise Therapeutics, Inc.Open in the cockpit ↗

Edgewise Therapeutics, Inc.EWTXCompetitor analysis, valuation and peers

United States · USD·Health Care›Biotechnology

Develops precision medicines for genetically defined muscle diseases including Duchenne muscular dystrophy and cardiomyopathies.

Momentum leader 83
Mkt cap
$4.89B
US dollars, full cap
Free float
75%
of shares outstanding
$/day
$65.4M
20-day average traded
Fwd P/E
n/m
no positive forecast
ROIC−WACC
n/a
WACC 6.8%
Hurdle
n/a
no reverse DCF
Next earnings
111 days
25 Feb 2027
Close · USD$45.04
1D+15.9%
1W+15.8%
1M+14.8%
3M+1.0%
6M+27.5%
YTD+81.5%
1Y+159.3%
ATR %6.1%
Beta1.04
52w lowhigh7.2% off high

What Edgewise Therapeutics does

Develops precision medicines for genetically defined muscle diseases including Duchenne muscular dystrophy and cardiomyopathies.

Has no approved product and so no sales; trial spending is funded by raising money from investors and from cash on hand. Any future income depends on regulators approving one of its medicines, which would then be sold to a small group of specialist doctors.

Products and services

  • Sevasemten (Duchenne/Becker muscular dystrophy)
  • EDG-7500 (hypertrophic cardiomyopathy)

Customers

  • Neuromuscular disease specialists
  • Cardiologists (post-approval)

Where it sits in the supply chain

  • Health Care
  • Biotechnology
  • Muscle-disease precision medicine

What could go right

  • Pivotal trial data readouts
  • Cardiomyopathy market expansion

What could go wrong

  • Clinical trial failure risk
  • Competitive muscular dystrophy treatment landscape

Moat: none (IP / patents). Clinical-stage biotech with novel muscle-targeted mechanisms but no approved products yet.

Headquarters: Boulder, Colorado, US · Founded: 2017 · Employees: 146

Named competitors

Edgewise Therapeutics at a glance

Size Edgewise Therapeutics (EWTX) is a United States Health Care company (Biotechnology) with a market value of $4.89B, the 1195th largest of 3,117 United States companies the cockpit tracks. Shares closed at $45.04 on 6 Nov 2026.

Performance Over six months the shares gained 27.5%, against -1.2% for the median peer and -1.1% for the United States market (cap-weighted) — 7th highest of 21 in its peer set.

Short interest Short interest is 10.8% of the free float (15 Oct 2026).

Next results Next results expected around 25 Feb 2027 (exchange calendar; dates can move).

Relative performance

10012014011 May 202611 Aug 20266 Nov 2026EWTX 130Peer median 98
Six months, rebased to 100: Edgewise Therapeutics against the median of its 20 peers (local-currency closes).

Edgewise Therapeutics financials

Reported figures in USD; fiscal year ends 2025-12-31. TTM = trailing twelve months.
TTMFY2025FY2024FY2023FY2022
Revenue$0$0$0$0$0
Revenue growth—————
Gross profit-$2.33M-$2.27M-$2.29M-$1.73M-$538,000
EBITDA-$217M-$189M-$157M-$113M-$71.1M
Net income-$197M-$168M-$134M-$100M-$67.6M
Free cash flow-$159M-$144M-$110M-$97.7M-$58.2M
Capital expenditure$454,000$256,000$1.31M$5.75M$5.55M
Total debt$3.59M$3.99M$4.74M$5.41M$4.41M

Quarterly statements and history in the cockpit →

Edgewise Therapeutics competitor charts

The default views of Competitor Analysis ▸ Charts, drawn from the same data. Open them in the cockpit to change the axes, pin companies and read every value.

Performance: 6-month against 1-month return

0%+50%+100%+150%0%+10%0022521530CRSPDNTH603392603127000661300122ADPTANTHEMCOGT300347SRRKRLAYABCLKODIMVT6696IOVAEWTX6-month return →1-month return →
Up and to the right = strong over both horizons. Edgewise Therapeutics is the large dot.

Edgewise Therapeutics competitors and peer comparison

Head to head with its named competitors (EWTX vs SRPT vs CYTK vs BBIO)
CompanyMarket cap6M returnRevenue growthOp. marginEV / SalesReq g
Edgewise Therapeutics EWTX$4.89B+28%n/an/an/an/a
Sarepta Therapeutics SRPT$1.88B-11%-20%-3%1.1×11.9%
Cytokinetics CYTK$7.46B-30%-21%-1,046%111.8×n/a
BridgeBio Pharma BBIO$14.5B+10%+167%-37%18.3×n/a

How Edgewise Therapeutics compares with its peers

Peer set: Industry: the same industry and sector in any market, nearest in size. This is the same default set the interactive Competitor Analysis opens with.

Edgewise Therapeutics against its 20 peers (data as of 6 Nov 2026)
MeasureEWTXPeer medianRank in peer set
1-month return+14.8%+2.1%2nd highest of 21
6-month return+27.5%-1.2%7th highest of 21
Distance from 52-week high-7.2%-24.0%4th highest of 21

Peer table

Peer set: Industry: the same industry and sector in any market, nearest in size
CompanyMarketMarket cap6M returnRevenue growthOp. marginEV / SalesReq gDelivered g
Edgewise Therapeutics EWTXUnited States$4.89B+28%n/an/an/an/an/a
Shanghai RAAS Blood Products 002252.SZChina$4.89B-11%-22%17%5.7×n/an/a
3SBio 1530.HKHong Kong$4.92B-34%+102%61%1.2×n/an/a
CRISPR Therapeutics CRSPUnited States$4.86B-9%-34%-2,059%133.6×n/an/a
Dianthus Therapeutics DNTHUnited States$4.81B-1%-61%-11,441%2,087.9×n/an/a
Beijing Wantai Biological Pharmacy Enterprise 603392.SSChina$4.72B-37%+8%-35%14.5×n/an/a
Joinn Laboratories (China) 603127.SSChina$4.58B+15%+12%-4%15.1×n/an/a
Changchun High-Tech Industry (Group) 000661.SZChina$4.51B-13%-18%-1%2.8×32.2%+7.1%
Chongqing Zhifei Biological Products 300122.SZChina$5.35B-2%-28%-210%5.4×-6.4%-10.0%
Adaptive Biotechnologies ADPTUnited States$4.47B+103%+50%-12%14.7×n/an/a
Anthem Biosciences ANTHEM.NSIndia$5.46B+17%-1%35%24.9×36.7%+26.2%
Cogent Biosciences COGTUnited States$5.49B-9%n/an/an/an/an/a
Hangzhou Tigermed Consulting 300347.SZChina$5.58B-6%+16%10%5.4×28.4%+16.4%
Scholar Rock SRRKUnited States$5.72B-3%n/an/an/an/an/a
Relay Therapeutics RLAYUnited States$4.08B+46%+24%-2,999%308.8×n/an/a
AbCellera Biologics ABCLUnited States$3.85B+149%+101%-340%51.7×n/an/a
Kodiak Sciences KODUnited States$6.24B+142%n/an/an/an/an/a
Immunovant IMVTUnited States$6.31B+5%n/an/an/an/an/a
Beijing Tiantan Biological Products 600161.SSChina$3.76B-11%-13%21%4.8×3.2%+12.5%
Lin BioScience 6696.TWOTaiwan$3.74B+129%n/an/an/an/an/a
Iovance Biotherapeutics IOVAUnited States$3.64B+64%+35%-91%10.4×n/an/a

Questions

Who are Edgewise Therapeutics's main competitors?
Named competitors: Sarepta Therapeutics (SRPT), PepGen (private or unlisted), Cytokinetics (CYTK), BridgeBio Pharma (BBIO). The cockpit's measured peer set (industry) also includes Shanghai RAAS Blood Products (002252.SZ), 3SBio (1530.HK), CRISPR Therapeutics (CRSP), Dianthus Therapeutics (DNTH), Beijing Wantai Biological Pharmacy Enterprise (603392.SS), Joinn Laboratories (China) (603127.SS).
How has Edgewise Therapeutics stock performed?
Over six months to 6 Nov 2026 the shares returned +27.5% against -1.2% for the median peer; over one year +159.3%.

How these numbers are made. Returns are close-to-close in local currency. Revenue growth and margins are trailing twelve months. Req g is the revenue growth that today's enterprise value requires for seven years at the company's own cost of capital; Delivered g is what it actually grew; the gap is the hurdle (honest precision about ±8 points, so read the ranking more than the decimal). No fair values, price targets or analyst ratings are shown, by design. Method and validation.