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← CockpitCompetitor Analysis › ANRO Alto Neuroscience, Inc.Open in the cockpit ↗

Alto Neuroscience, Inc.ANROCompetitor analysis, valuation and peers

United States · USD·Health Care›Biotechnology

Uses biomarker-based patient selection to develop precision psychiatric drugs matched to specific patient subtypes.

Momentum neutral 50
Mkt cap
$987M
US dollars, full cap
Free float
91%
of shares outstanding
$/day
$13.9M
20-day average traded
Fwd P/E
n/m
no positive forecast
ROIC−WACC
n/a
WACC 11.9%
Hurdle
n/a
no reverse DCF
Next earnings
5 days
11 Nov 2026
Close · USD$25.16
1D+15.0%
1W+11.3%
1M+4.7%
3M-11.1%
6M+3.7%
YTD+41.4%
1Y+122.8%
ATR %6.5%
Beta1.64
52w lowhigh32.9% off high

What Alto Neuroscience does

Uses biomarker-based patient selection to develop precision psychiatric drugs matched to specific patient subtypes.

Pre-revenue: it sells nothing, and trial costs are paid from cash raised since its early-2024 listing. Each drug is tested only in patients whose brain-activity or other markers match, so the results of those mid-stage depression trials, not sales, decide the company's course.

Products and services

  • ALTO-100 (major depressive disorder)
  • ALTO-300 (biomarker-selected depression)

Customers

  • Psychiatrists (post-approval)

Where it sits in the supply chain

  • Health Care
  • Biotechnology
  • Precision psychiatry drug development

What could go right

  • Improved trial success odds via biomarker selection
  • Large underserved psychiatric drug market

What could go wrong

  • Clinical trial failure risk
  • Unproven biomarker-selection approach at scale

Moat: narrow (data, process know-how). Proprietary biomarker/EEG-based patient stratification aims to improve historically poor psychiatric trial success rates.

Headquarters: Los Altos, California, US · Founded: 2019 · Employees: 68

Named competitors

Alto Neuroscience at a glance

Size Alto Neuroscience (ANRO) is a United States Health Care company (Biotechnology) with a market value of $987M, the 2256th largest of 3,117 United States companies the cockpit tracks. Shares closed at $25.16 on 6 Nov 2026.

Performance Over six months the shares gained 3.7%, against -10.9% for the median peer and -1.1% for the United States market (cap-weighted) — 4th highest of 20 in its peer set.

Short interest Short interest is 13.3% of the free float (15 Oct 2026).

Next results Next results expected around 11 Nov 2026 (exchange calendar; dates can move).

Relative performance

7510012515011 May 202611 Aug 20266 Nov 2026ANRO 103Peer median 88
Six months, rebased to 100: Alto Neuroscience against the median of its 20 peers (local-currency closes).

Alto Neuroscience financials

Reported figures in USD; fiscal year ends 2025-12-31. TTM = trailing twelve months.
TTMFY2025FY2024FY2023FY2022
Revenue$0$0$0$0$0
Revenue growth—————
Gross profit-$705,000-$661,000-$502,000-$373,000-$342,000
EBITDA-$87.6M-$65.7M-$68.1M-$37.4M-$28.9M
Net income-$84.2M-$63.2M-$61.4M-$36.3M-$27.7M
Free cash flow-$68.8M-$51.8M-$49.5M-$33.9M-$21.1M
Capital expenditure$556,000$24,000$2.08M$470,000$732,000
Total debt$23.3M$24.0M$16.9M$151M$82.1M

Quarterly statements and history in the cockpit →

Alto Neuroscience competitor charts

The default views of Competitor Analysis ▸ Charts, drawn from the same data. Open them in the cockpit to change the axes, pin companies and read every value.

Performance: 6-month against 1-month return

-50%0%+50%-25%0%+25%300841688276JBIOVSTM9887IVAJANXGLUEOXB0020302160SNDX4587PRMERAPPANRO6-month return →1-month return →
Up and to the right = strong over both horizons. Alto Neuroscience is the large dot.

Alto Neuroscience competitors and peer comparison

Head to head with its named competitors (ANRO vs NBIX)
CompanyMarket cap6M returnRevenue growthOp. marginEV / SalesReq g
Alto Neuroscience ANRO$987M+4%n/an/an/an/a
Neurocrine Biosciences NBIX$16.7B+8%+38%25%4.4×-1.7%

How Alto Neuroscience compares with its peers

Peer set: Industry: the same industry and sector in any market, nearest in size. This is the same default set the interactive Competitor Analysis opens with.

Alto Neuroscience against its 20 peers (data as of 6 Nov 2026)
MeasureANROPeer medianRank in peer set
1-month return+4.7%-4.6%6th highest of 21
6-month return+3.7%-10.9%4th highest of 20
Distance from 52-week high-32.9%-41.7%5th highest of 21

Peer table

Peer set: Industry: the same industry and sector in any market, nearest in size
CompanyMarketMarket cap6M returnRevenue growthOp. marginEV / SalesReq gDelivered g
Alto Neuroscience ANROUnited States$987M+4%n/an/an/an/an/a
Chengdu Kanghua Biological Products Co. Td Class 1 300841.SZChina$995M-11%0%22%4.7×11.1%+2.3%
Changchun BCHT Biotechnology 688276.SSChina$1.00B-11%+2%-29%10.0×n/an/a
China Animal Husbandry Industry 600195.SSChina$960M-17%+1%2%1.4×6.6%+4.4%
Jade Biosciences JBIOUnited States$958M-42%n/an/an/an/an/a
Innovita Biological Technology 688253.SSChina$1.02B-4%-28%11%16.3×42.9%-16.6%
Verastem VSTMUnited States$1.02B+72%+3,996%-183%11.1×n/an/a
Nanjing Leads Biolabs 9887.HKHong Kong$927M-54%n/a-108%26.5×n/an/a
Odyssey Therapeutics ODTXUnited States$924Mn/a-33%-5,415%208.9×n/an/a
Inventiva IVA.PAFrance$912M-29%-100%-307,063%14,560.9×n/an/a
Janux Therapeutics JANXUnited States$1.08B+24%+5,367%-598%5.3×n/an/a
Monte Rosa Therapeutics GLUEUnited States$902M-45%-84%-633%11.1×n/an/a
Oxford BioMedica OXB.LUnited Kingdom$892M-14%+16%-18%4.3×n/an/a
Daan Gene 002030.SZChina$1.11B-9%+1%-81%8.4×5.7%-32.3%
GNI 2160.TJapan$866M-29%+10%-24%5.7×n/an/a
MeiraGTx MGTXUnited States$864M-8%+948%46%2.1×-9.9%+39.2%
Syndax Pharmaceuticals SNDXUnited States$859M-56%+160%-62%3.5×n/an/a
Peptidream 4587.TJapan$856M-10%+1%-25%6.6×n/an/a
Guangzhou Wondfo Biotech 300482.SZChina$1.14B-10%-24%-2%3.2×16.4%-5.8%
Prime Medicine PRMEUnited States$843M+45%-18%-4,825%211.3×n/an/a
Rapport Therapeutics RAPPUnited States$1.17B-36%n/a-838%39.3×n/an/a

Questions

Who are Alto Neuroscience's main competitors?
Named competitors: Sage Therapeutics (private or unlisted), Neurocrine Biosciences (NBIX). The cockpit's measured peer set (industry) also includes Chengdu Kanghua Biological Products Co. Td Class 1 (300841.SZ), Changchun BCHT Biotechnology (688276.SS), China Animal Husbandry Industry (600195.SS), Jade Biosciences (JBIO), Innovita Biological Technology (688253.SS), Verastem (VSTM).
How has Alto Neuroscience stock performed?
Over six months to 6 Nov 2026 the shares returned +3.7% against -10.9% for the median peer; over one year +122.8%.

How these numbers are made. Returns are close-to-close in local currency. Revenue growth and margins are trailing twelve months. Req g is the revenue growth that today's enterprise value requires for seven years at the company's own cost of capital; Delivered g is what it actually grew; the gap is the hurdle (honest precision about ±8 points, so read the ranking more than the decimal). No fair values, price targets or analyst ratings are shown, by design. Method and validation.