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← CockpitCompetitor Analysis › WVE Wave Life Sciences Ltd.Open in the cockpit ↗

Wave Life Sciences Ltd.WVECompetitor analysis, valuation and peers

United States · USD·Health Care›Biotechnology
Momentum laggard 9
Mkt cap
$664M
US dollars, full cap
Free float
84%
of shares outstanding
$/day
$10.5M
20-day average traded
Fwd P/E
n/m
no positive forecast
ROIC−WACC
n/a
WACC 6.3%
Hurdle
n/a
no reverse DCF
Next earnings
118 days
4 Mar 2027
Close · USD$3.37
1D+4.5%
1W-6.3%
1M-3.0%
3M-44.6%
6M-53.1%
YTD-80.2%
1Y-58.1%
ATR %6.9%
Beta1.30
52w lowhigh84.5% off high

What Wave Life Sciences does

Employees: 317

Wave Life Sciences at a glance

Size Wave Life Sciences (WVE) is a United States Health Care company (Biotechnology) with a market value of $664M, the 2526th largest of 3,117 United States companies the cockpit tracks. Shares closed at $3.37 on 6 Nov 2026.

Performance Over six months the shares fell 53.1%, against -18.8% for the median peer and -1.1% for the United States market (cap-weighted) — 2nd lowest of 19 in its peer set.

Growth Revenue fell 35.1% over the last twelve months (peer median +27.7%); the operating margin is -320.9% (peer median -111.2%).

Valuation It trades at 3.9× enterprise value to sales against a peer median of 8.0× (6th cheapest of 15).

Short interest Short interest is 10.7% of the free float (15 Oct 2026).

Next results Next results expected around 4 Mar 2027 (exchange calendar; dates can move).

Relative performance

507510011 May 202611 Aug 20266 Nov 2026Peer median 82WVE 48
Six months, rebased to 100: Wave Life Sciences against the median of its 20 peers (local-currency closes).

Wave Life Sciences financials

Reported figures in USD; fiscal year ends 2025-12-31. TTM = trailing twelve months.
TTMFY2025FY2024FY2023FY2022
Revenue$70.9M$42.7M$108M$113M$3.65M
Revenue growth—-61%-4%+3,005%—
Gross profit$61.7M$33.9M$99.6M$104M-$6.46M
EBITDA-$218M-$207M-$102M-$58.8M-$153M
Net income-$211M-$204M-$97.0M-$57.5M-$162M
Free cash flow-$206M-$188M-$152M-$20.5M-$129M
Capital expenditure$1.33M$718,000$938,000$1.11M$1.36M
Total debt$43.3M$17.8M$25.4M$32.1M$37.6M

Quarterly statements and history in the cockpit →

Wave Life Sciences competitor charts

The default views of Competitor Analysis ▸ Charts, drawn from the same data. Open them in the cockpit to change the axes, pin companies and read every value.

Performance: 6-month against 1-month return

0%+200%+400%+600%+800%-50%-25%0%+25%300404CADLFDMTAURA603387KURA002880ATTO1672GNFTWVE6-month return →1-month return →
Up and to the right = strong over both horizons. Wave Life Sciences is the large dot.

Fundamentals: revenue growth against valuation

0%+100,000%+200,000%+300,000%0×1,000×2,000×300404FDMT6033871672WVERevenue growth (TTM) →EV / Sales →
Further right = faster growth; higher = more expensive. The dashed lines are the peer medians. Wave Life Sciences is the large dot.

Wave Life Sciences competitors and peer comparison

How Wave Life Sciences compares with its peers

Peer set: Industry: the same industry and sector in any market, nearest in size. This is the same default set the interactive Competitor Analysis opens with.

Wave Life Sciences against its 20 peers (data as of 6 Nov 2026)
MeasureWVEPeer medianRank in peer set
1-month return-3.0%-10.5%4th highest of 21
6-month return-53.1%-18.8%2nd lowest of 19
Distance from 52-week high-84.5%-43.2%lowest of 21
Revenue growth (TTM)-35.1%+27.7%2nd lowest of 14
Operating margin-320.9%-111.2%5th lowest of 15
EV / Sales3.9×8.0×6th cheapest of 15

Peer table

Peer set: Industry: the same industry and sector in any market, nearest in size
CompanyMarketMarket cap6M returnRevenue growthOp. marginEV / SalesReq gDelivered g
Wave Life Sciences WVEUnited States$664M-53%-35%-321%3.9×n/an/a
Boji Medical Technology 300404.SZChina$664M+7%+32%4%4.1×35.4%+27.2%
Candel Therapeutics CADLUnited States$670M+5%n/an/an/an/an/a
4D Molecular Therapeutics FDMTUnited States$677M+21%+278,712%-214%3.9×n/an/a
Aura Biosciences AURAUnited States$680M-22%n/an/an/an/an/a
Getein Biotech 603387.SSChina$647M-12%+8%21%2.7×-8.3%-1.3%
Kura Oncology KURAUnited States$647M-23%-7%-412%2.0×n/an/a
Shenzhen Weiguang Biological Products 002880.SZChina$682M-22%0%18%4.7×n/an/a
Anhui Huaheng Biotechnology 688639.SSChina$688M-40%+7%3%2.1×n/an/a
Design Therapeutics DSGNUnited States$639M-28%n/an/an/an/an/a
Geron GERNUnited States$636M-29%+19%-8%1.6×n/an/a
Attovia Therapeutics ATTOUnited States$697M+744%n/a-4,975%625.6×n/an/a
Apnimed APMDUnited States$629Mn/a+380%-140%20.3×n/an/a
Solid Biosciences SLDBUnited States$707M-9%n/an/an/an/an/a
Sana Biotechnology SANAUnited States$709M-32%n/an/an/an/an/a
Ascletis Pharma 1672.HKHong Kong$610M-73%-59%-71,976%2,088.7×n/an/a
Shouyao Holdings Beijing 688197.SSChina$726M-16%+4,564%-92%43.1×n/an/a
Genfit GNFT.PAFrance$593M+19%+28%-130%11.2×40.0%+143.5%
Climb Bio CLYMUnited States$591M-10%n/an/an/an/an/a
Frontier Biotechnologies 688221.SSChina$746M-37%+153%-20%13.1×43.2%+21.5%
Alebund Pharmaceuticals (Jiangsu) 9637.HKHong Kong$576Mn/a+674%-495%25.7×n/an/a

Questions

Which companies are Wave Life Sciences's closest peers?
The cockpit's peer set: Boji Medical Technology (300404.SZ), Candel Therapeutics (CADL), 4D Molecular Therapeutics (FDMT), Aura Biosciences (AURA), Getein Biotech (603387.SS), Kura Oncology (KURA), Shenzhen Weiguang Biological Products (002880.SZ), Anhui Huaheng Biotechnology (688639.SS).
Is Wave Life Sciences expensive compared with its peers?
On ev / sales it trades at 3.9× against a peer median of 8.0×, 6th cheapest of 15 in its peer set.
How has Wave Life Sciences stock performed?
Over six months to 6 Nov 2026 the shares returned -53.1% against -18.8% for the median peer; over one year -58.1%.

How these numbers are made. Returns are close-to-close in local currency. Revenue growth and margins are trailing twelve months. Req g is the revenue growth that today's enterprise value requires for seven years at the company's own cost of capital; Delivered g is what it actually grew; the gap is the hurdle (honest precision about ±8 points, so read the ranking more than the decimal). No fair values, price targets or analyst ratings are shown, by design. Method and validation.