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← CockpitCompetitor Analysis › NUVB Nuvation Bio, Inc. Class AOpen in the cockpit ↗

Nuvation Bio, Inc. Class ANUVBCompetitor analysis, valuation and peers

United States · USD·Health Care›Biotechnology

Develops targeted oncology therapies, including an approved treatment for a rare form of lung cancer (Ibtrozi).

Momentum laggard 17
Mkt cap
$1.46B
US dollars, full cap
Free float
72%
of shares outstanding
$/day
$24.2M
20-day average traded
Fwd P/E
n/m
no positive forecast
ROIC−WACC
n/a
WACC 11.7%
Hurdle
n/a
no reverse DCF
Next earnings
125 days
11 Mar 2027
Close · USD$4.16
1D-0.7%
1W-12.6%
1M-16.0%
3M-37.0%
6M-13.2%
YTD-53.6%
1Y-15.4%
ATR %6.7%
Beta1.66
52w lowhigh57.3% off high

What Nuvation Bio does

Develops targeted oncology therapies, including an approved treatment for a rare form of lung cancer (Ibtrozi).

Its marketed drug Ibtrozi, approved in the US in 2025, came through the 2024 purchase of AnHeart Therapeutics, and product revenue starts from that launch. Oncologists prescribe it for patients whose tumours carry a ROS1 gene change, and it uses cash and launch revenue to fund the rest of its pipeline.

Products and services

  • Ibtrozi/taletrectinib (ROS1+ lung cancer)
  • Oncology pipeline (safusidenib and other targets)

Customers

  • Oncologists/cancer centers

Where it sits in the supply chain

  • Health Care
  • Biotechnology
  • Targeted oncology therapeutics

What could go right

  • Taletrectinib commercial launch and uptake
  • Pipeline diversification

What could go wrong

  • Competitive ROS1-targeted therapy market
  • Commercial launch execution risk

Moat: none (IP / patents, regulatory licence). Newly approved targeted therapy for a genetically defined lung cancer subtype, in a competitive class.

Headquarters: New York City, US · Founded: 2018 · Employees: 298

Named competitors

Nuvation Bio at a glance

Size Nuvation Bio (NUVB) is a United States Health Care company (Biotechnology) with a market value of $1.46B, the 2005th largest of 3,117 United States companies the cockpit tracks. Shares closed at $4.16 on 6 Nov 2026.

Performance Over six months the shares fell 13.2%, against -19.4% for the median peer and -1.1% for the United States market (cap-weighted) — 7th highest of 18 in its peer set.

Growth Revenue grew 1,083.6% over the last twelve months (peer median +21.1%); the operating margin is -81.0% (peer median -26.7%).

Valuation It trades at 7.2× enterprise value to sales against a peer median of 19.4× (7th cheapest of 16).

Credit Nuvation Bio has 1 bond outstanding ($288M).

Short interest Short interest is 18.0% of the free float (15 Oct 2026).

Next results Next results expected around 11 Mar 2027 (exchange calendar; dates can move).

Relative performance

7510012515011 May 202611 Aug 20266 Nov 2026NUVB 87Peer median 80
Six months, rebased to 100: Nuvation Bio against the median of its 20 peers (local-currency closes).

Nuvation Bio financials

Reported figures in USD; fiscal year ends 2025-12-31. TTM = trailing twelve months.
TTMFY2025FY2024FY2023FY2022
Revenue$170M$62.9M$7.87M$0$0
Revenue growth—+699%———
Gross profit$148M$51.9M$112,000-$222,000-$484,000
EBITDA-$135M-$211M-$167M-$99.6M-$119M
Net income-$150M-$205M-$568M-$75.8M-$104M
Free cash flow-$121M-$174M-$131M-$68.1M-$96.5M
Capital expenditure$8.40M$8.35M$162,000$69,000$370,000
Total debt$416M$213M$8.91M$4.01M$4.26M

Quarterly statements and history in the cockpit →

Nuvation Bio competitor charts

The default views of Competitor Analysis ▸ Charts, drawn from the same data. Open them in the cockpit to change the axes, pin companies and read every value.

Performance: 6-month against 1-month return

-50%0%+50%+100%+150%0%+50%TYRA6949QUREKRSATSHA3012074588MLYSIMCRPGENPPGNNUVB6-month return →1-month return →
Up and to the right = strong over both horizons. Nuvation Bio is the large dot.

Fundamentals: revenue growth against valuation

0%+500%+1,000%+1,500%+2,000%0×500×1,000×1,500×6949QUREKRSA145020TSHA4588688806PGENNUVBRevenue growth (TTM) →EV / Sales →
Further right = faster growth; higher = more expensive. The dashed lines are the peer medians. Nuvation Bio is the large dot.

Nuvation Bio competitors and peer comparison

Head to head with its named competitors (NUVB vs RO.SW vs BMY)
CompanyMarket cap6M returnRevenue growthOp. marginEV / SalesReq g
Nuvation Bio NUVB$1.46B-13%+1,084%-81%7.2×n/a
Roche RO.SW$385B+22%-1%31%5.6×0.9%
Bristol Myers Squibb BMY$127B+12%+4%33%3.2×-12.9%

How Nuvation Bio compares with its peers

Peer set: Industry: the same industry and sector in any market, nearest in size. This is the same default set the interactive Competitor Analysis opens with.

Nuvation Bio against its 20 peers (data as of 6 Nov 2026)
MeasureNUVBPeer medianRank in peer set
1-month return-16.0%-3.0%5th lowest of 21
6-month return-13.2%-19.4%7th highest of 18
Distance from 52-week high-57.3%-40.7%3rd lowest of 21
Revenue growth (TTM)+1,083.6%+21.1%3rd highest of 17
Operating margin-81.0%-26.7%8th lowest of 17
EV / Sales7.2×19.4×7th cheapest of 16

Peer table

Peer set: Industry: the same industry and sector in any market, nearest in size
CompanyMarketMarket cap6M returnRevenue growthOp. marginEV / SalesReq gDelivered g
Nuvation Bio NUVBUnited States$1.46B-13%+1,084%-81%7.2×n/an/a
Tyra Bioscience TYRAUnited States$1.45B-38%n/an/an/an/an/a
Kardigan KARDUnited States$1.45Bn/an/an/an/an/an/a
PELL Bio-Med Technology 6949.TWTaiwan$1.49B+126%+5%-1,720%1,640.0×n/an/a
uniQure QUREUnited States$1.51B-22%+30%-1,093%66.8×n/an/a
Korsana Biosciences KRSAUnited States$1.41B+43%-13%-359%743.5×n/an/a
Hugel 145020.KSSouth Korea$1.52B-26%+17%38%4.4×-7.9%+15.0%
Taysha Gene Therapies TSHAUnited States$1.41B-36%-32%-2,855%184.6×n/an/a
Fujian Haixi Pharmaceuticals 2637.HKHong Kong$1.53B-41%+25%33%n/an/an/a
Hualan Biological Vaccine 301207.SZChina$1.39B-21%-28%-7%10.3×36.5%-13.1%
AnaptysBio ANABUnited States$1.39B-33%+93%56%6.3×-1.2%+25.6%
Oncolys BioPharma 4588.TJapan$1.39B+162%+1,662%-303%429.8×n/an/a
ANI Pharmaceuticals ANIPUnited States$1.55B-18%+31%13%1.8×-4.1%+33.5%
Pacific Shuanglin Bio-pharmacy 000403.SZChina$1.38B-19%+1%10%3.8×n/an/a
TLC BioSciences 7924.TWOTaiwan$1.57Bn/an/an/an/an/an/a
Zhuhai Trinomab Pharmaceutical 688806.SSChina$1.58Bn/a+238%-1,196%199.0×n/an/a
Mineralys Therapeutics MLYSUnited States$1.36B-48%n/an/an/an/an/a
Intellia Therapeutics NTLAUnited States$1.59B-19%+13%-712%20.6×n/an/a
Immunocore Holdings Plc Shs Sponsored American Depositary Shares Repr 1 Sh IMCRUnited States$1.60B+5%+20%-5%2.7×n/an/a
Precigen PGENUnited States$1.60B+6%+1,875%-46%19.4×n/an/a
PolyPeptide PPGN.SWSwitzerland$1.62B+6%+22%7%3.3×n/an/a

Nuvation Bio bonds and credit

Nuvation Bio has 1 bond outstanding with $288M face value.

Every bond, yield and spread in the cockpit →

Questions

Who are Nuvation Bio's main competitors?
Named competitors: Roche (Rozlytrek) (RO.SW), Bristol Myers Squibb (Augtyro) (BMY). The cockpit's measured peer set (industry) also includes Tyra Bioscience (TYRA), Kardigan (KARD), PELL Bio-Med Technology (6949.TW), uniQure (QURE), Korsana Biosciences (KRSA), Hugel (145020.KS).
Is Nuvation Bio expensive compared with its peers?
On ev / sales it trades at 7.2× against a peer median of 19.4×, 7th cheapest of 16 in its peer set.
How has Nuvation Bio stock performed?
Over six months to 6 Nov 2026 the shares returned -13.2% against -19.4% for the median peer; over one year -15.4%.

How these numbers are made. Returns are close-to-close in local currency. Revenue growth and margins are trailing twelve months. Req g is the revenue growth that today's enterprise value requires for seven years at the company's own cost of capital; Delivered g is what it actually grew; the gap is the hurdle (honest precision about ±8 points, so read the ranking more than the decimal). No fair values, price targets or analyst ratings are shown, by design. Method and validation.