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← CockpitCompetitor Analysis › LXRX Lexicon Pharmaceuticals, Inc.Open in the cockpit ↗

Lexicon Pharmaceuticals, Inc.LXRXCompetitor analysis, valuation and peers

United States · USD·Health Care›Pharmaceuticals: Major
Momentum weak 29
Mkt cap
$792M
US dollars, full cap
Free float
49%
of shares outstanding
$/day
$3.11M
20-day average traded
Fwd P/E
n/m
no positive forecast
ROIC−WACC
-109.8 pp
WACC 10.0%
Hurdle
n/a
no reverse DCF
Next earnings
125 days
11 Mar 2027
Close · USD$1.78
1D+10.6%
1W+25.4%
1M+1.1%
3M-25.8%
6M-11.0%
YTD+54.8%
1Y+29.0%
ATR %5.9%
Beta1.13
52w lowhigh33.6% off high

What Lexicon Pharmaceuticals does

Employees: 81

Lexicon Pharmaceuticals at a glance

Size Lexicon Pharmaceuticals (LXRX) is a United States Health Care company (Pharmaceuticals: Major) with a market value of $792M, the 2403rd largest of 3,117 United States companies the cockpit tracks. Shares closed at $1.78 on 6 Nov 2026.

Performance Over six months the shares fell 11.0%, against -8.0% for the median peer and -1.1% for the United States market (cap-weighted) — 9th lowest of 20 in its peer set.

Growth Revenue fell 29.0% over the last twelve months (peer median +2.7%); the operating margin is -131.4% (peer median 10.1%).

Valuation It trades at 15.9× enterprise value to sales against a peer median of 2.4× (4th most expensive of 19).

Capital Return on invested capital runs 109.8 points below its cost of capital (10.0% WACC).

Next results Next results expected around 11 Mar 2027 (exchange calendar; dates can move).

Relative performance

608010011 May 202611 Aug 20266 Nov 2026Peer median 91LXRX 77
Six months, rebased to 100: Lexicon Pharmaceuticals against the median of its 20 peers (local-currency closes).

Lexicon Pharmaceuticals financials

Reported figures in USD; fiscal year ends 2025-12-31. TTM = trailing twelve months.
TTMFY2025FY2024FY2023FY2022
Revenue$41.5M$49.8M$31.1M$1.20M$139,000
Revenue growth—+60%+2,481%+766%—
Gross profit$40.6M$48.9M$29.9M$565,000-$288,000
EBITDA-$54.0M-$48.3M-$184M-$171M-$100M
Net income-$61.1M-$50.3M-$200M-$177M-$102M
Free cash flow-$65.0M-$67.9M-$181M-$162M-$90.2M
Capital expenditure$0$0$1.03M$470,000$1.33M
Total debt$59.2M$62.2M$106M$106M$55.3M

Quarterly statements and history in the cockpit →

Lexicon Pharmaceuticals competitor charts

The default views of Competitor Analysis ▸ Charts, drawn from the same data. Open them in the cockpit to change the axes, pin companies and read every value.

Performance: 6-month against 1-month return

-50%-25%0%+25%+50%-20%0%+20%SUVEN3001300705COLLANNX600479SANOFIGUD002940006120ALMS00239068856600290768865808645005700023492171LXRX6-month return →1-month return →
Up and to the right = strong over both horizons. Lexicon Pharmaceuticals is the large dot.

Fundamentals: revenue growth against valuation

-50%0%+50%0×250×500×750×SUVEN3001300705COLLGUD006120ALMS05702171LXRXRevenue growth (TTM) →EV / Sales →
Further right = faster growth; higher = more expensive. The dashed lines are the peer medians. Lexicon Pharmaceuticals is the large dot.

Lexicon Pharmaceuticals competitors and peer comparison

How Lexicon Pharmaceuticals compares with its peers

Peer set: Industry: the same industry and sector in any market, nearest in size. This is the same default set the interactive Competitor Analysis opens with.

Lexicon Pharmaceuticals against its 20 peers (data as of 6 Nov 2026)
MeasureLXRXPeer medianRank in peer set
1-month return+1.1%-3.6%9th highest of 20
6-month return-11.0%-8.0%9th lowest of 20
Distance from 52-week high-33.6%-30.4%9th lowest of 20
Revenue growth (TTM)-29.0%+2.7%2nd lowest of 19
Operating margin-131.4%10.1%4th lowest of 19
EV / Sales15.9×2.4×4th most expensive of 19
ROIC minus cost of capital-109.8 pp+1.6 pplowest of 17

Peer table

Peer set: Industry: the same industry and sector in any market, nearest in size
CompanyMarketMarket cap6M returnRevenue growthOp. marginEV / SalesReq gDelivered g
Lexicon Pharmaceuticals LXRXUnited States$792M-11%-29%-131%15.9×n/an/a
Suven Life Sciences SUVEN.NSIndia$792M+20%+17%-4,228%849.2×n/an/a
Katakura Industries 3001.TJapan$791M+46%0%16%2.5×0.2%+0.5%
Hunan Jiudian Pharmaceutical 300705.SZChina$789M-18%-5%13%1.9×-1.1%+26.1%
Collegium Pharmaceutical COLLUnited States$788M-36%+14%20%2.3×-7.0%+20.3%
Annexon ANNXUnited States$796M-26%n/an/an/an/an/a
Zhuzhou Qianjin Pharmaceutical 600479.SSChina$787M-3%+4%11%1.4×-1.4%0.0%
Sanofi India SANOFI.NSIndia$800M-3%-6%26%4.2×16.5%-8.7%
Knight Therapeutics GUD.TOCanada$800M+37%+42%5%1.9×9.5%+17.7%
Zhejiang Anglikang Pharmaceutical 002940.SZChina$801M-19%-6%10%4.2×18.2%+2.1%
Bambusa Therapeutics BBTXUnited States$783Mn/an/an/an/an/an/a
SK Discovery 006120.KSSouth Korea$804M+11%+20%3%0.8×n/an/a
Alumis ALMSUnited States$805M-27%-63%-5,480%45.8×n/an/a
Guizhou Xinbang Pharmaceutical 002390.SZChina$805M-10%-13%4%0.9×-3.0%-0.8%
Jiangsu Jibeier Pharmaceutical 688566.SSChina$777M-8%+9%24%4.3×11.5%+11.3%
Chongqing Pharscin Pharmaceutical 002907.SZChina$808M-7%+8%10%5.7×10.7%-1.4%
Youcare Pharmaceutical 688658.SSChina$776M-41%-7%-13%2.0×n/an/a
DongKook Pharmaceutical 086450.KSSouth Korea$776M-1%+13%10%1.1×-6.3%+10.6%
China Traditional Chinese Medicine 0570.HKHong Kong$771M-29%-16%0%0.4×n/an/a
Jinghua Pharmaceutical 002349.SZChina$825M-8%+2%20%3.2×-1.8%+2.6%
CARsgen Therapeutics 2171.HKHong Kong$825M-54%+68%-170%32.3×n/an/a

Questions

Which companies are Lexicon Pharmaceuticals's closest peers?
The cockpit's peer set: Suven Life Sciences (SUVEN.NS), Katakura Industries (3001.T), Hunan Jiudian Pharmaceutical (300705.SZ), Collegium Pharmaceutical (COLL), Annexon (ANNX), Zhuzhou Qianjin Pharmaceutical (600479.SS), Sanofi India (SANOFI.NS), Knight Therapeutics (GUD.TO).
Is Lexicon Pharmaceuticals expensive compared with its peers?
On ev / sales it trades at 15.9× against a peer median of 2.4×, 4th most expensive of 19 in its peer set.
How has Lexicon Pharmaceuticals stock performed?
Over six months to 6 Nov 2026 the shares returned -11.0% against -8.0% for the median peer; over one year +29.0%.

How these numbers are made. Returns are close-to-close in local currency. Revenue growth and margins are trailing twelve months. Req g is the revenue growth that today's enterprise value requires for seven years at the company's own cost of capital; Delivered g is what it actually grew; the gap is the hurdle (honest precision about ±8 points, so read the ranking more than the decimal). No fair values, price targets or analyst ratings are shown, by design. Method and validation.