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← CockpitCompetitor Analysis › GHRS GH Research PlcOpen in the cockpit ↗

GH Research PlcGHRSCompetitor analysis, valuation and peers

United States · USD·Health Care›Pharmaceuticals: Major

Clinical-stage biotech developing fast-acting psychedelic-derived (5-MeO-DMT) treatments for treatment-resistant depression.

Momentum laggard 19
Mkt cap
$1.28B
US dollars, full cap
Free float
74%
of shares outstanding
$/day
$6.82M
20-day average traded
Fwd P/E
n/m
no positive forecast
ROIC−WACC
n/a
WACC 11.4%
Hurdle
n/a
no reverse DCF
Next earnings
118 days
4 Mar 2027
Close · USD$18.61
1D+0.9%
1W-10.8%
1M-9.0%
3M-37.0%
6M-13.1%
YTD+46.5%
1Y+36.9%
ATR %6.9%
Beta1.35
52w lowhigh40.8% off high

What GH Research does

Clinical-stage biotech developing fast-acting psychedelic-derived (5-MeO-DMT) treatments for treatment-resistant depression.

Has no medicine on sale, so it funds trials from money raised from investors, and revenue would arrive only after approval or a licensing deal. The business rests on one lead drug in one form of depression, so trial results move the whole company.

Products and services

  • GH001 (inhaled mebufotenin, TRD)
  • Other 5-MeO-DMT formulations

Where it sits in the supply chain

  • Biopharma R&D
  • Psychedelic-derived neuropsychiatric…
  • Clinical trials for depression

What could go right

  • Positive pivotal trial data
  • First-mover in fast-acting psychedelic therapy

What could go wrong

  • Regulatory novelty/scheduling risk
  • Binary clinical trial risk

Moat: none (IP / patents). Pre-commercial; must navigate a novel regulatory path for a psychedelic-derived psychiatric drug.

Headquarters: Dublin, Ireland · Founded: 2018 · Employees: 73

Named competitors

GH Research at a glance

Size GH Research (GHRS) is a United States Health Care company (Pharmaceuticals: Major) with a market value of $1.28B, the 2096th largest of 3,117 United States companies the cockpit tracks. Shares closed at $18.61 on 6 Nov 2026.

Performance Over six months the shares fell 13.1%, against -10.9% for the median peer and -1.1% for the United States market (cap-weighted) — 10th lowest of 21 in its peer set.

Short interest Short interest is 2.9% of the free float (15 Oct 2026).

Next results Next results expected around 4 Mar 2027 (exchange calendar; dates can move).

Relative performance

10012014011 May 202611 Aug 20266 Nov 2026Peer median 88GHRS 88
Six months, rebased to 100: GH Research against the median of its 20 peers (local-currency closes).

GH Research financials

Reported figures in USD; fiscal year ends 2025-12-31. TTM = trailing twelve months.
TTMFY2025FY2024FY2023FY2022
Revenue$0$0$0$0$0
Revenue growth—————
Gross profit-$359,000-$335,000-$315,000-$315,000-$47,000
EBITDA-$71.1M-$60.3M-$49.9M-$40.9M-$30.5M
Net income-$62.3M-$48.3M-$39.0M-$35.6M-$22.5M
Free cash flow-$52.5M-$43.7M-$42.3M-$33.4M-$26.3M
Capital expenditure$139,151$121,000$49,000$100,000$67,000
Total debt$360,000$512,000$624,000$974,000$0

Quarterly statements and history in the cockpit →

GH Research competitor charts

The default views of Competitor Analysis ▸ Charts, drawn from the same data. Open them in the cockpit to change the axes, pin companies and read every value.

Performance: 6-month against 1-month return

-60%-40%-20%0%+20%-20%0%347850NKTRPYC068760AVLN226950MNKD310210688076000950OMER00942017951952IDIA002332688443PAHC688293GHRS6-month return →1-month return →
Up and to the right = strong over both horizons. GH Research is the large dot.

GH Research competitors and peer comparison

Head to head with its named competitors (GHRS vs CMPS vs ATAI vs JNJ)
CompanyMarket cap6M returnRevenue growthOp. marginEV / SalesReq g
GH Research GHRS$1.28B-13%n/an/an/an/a
COMPASS Pathways Plc Sponsored ADR CMPS$1.22B-13%n/an/an/an/a
AtaiBeckley ATAIn/a+81%n/an/an/an/a
Johnson & Johnson JNJ$665B+26%+8%26%7.0×3.5%

How GH Research compares with its peers

Peer set: Industry: the same industry and sector in any market, nearest in size. This is the same default set the interactive Competitor Analysis opens with.

GH Research against its 20 peers (data as of 6 Nov 2026)
MeasureGHRSPeer medianRank in peer set
1-month return-9.0%-6.2%9th lowest of 21
6-month return-13.1%-10.9%10th lowest of 21
Distance from 52-week high-40.8%-42.6%11th highest of 21

Peer table

Peer set: Industry: the same industry and sector in any market, nearest in size
CompanyMarketMarket cap6M returnRevenue growthOp. marginEV / SalesReq gDelivered g
GH Research GHRSUnited States$1.28B-13%n/an/an/an/an/a
D&D Pharmatech 347850.KSSouth Korea$1.28B-49%-71%-1,368%617.6×n/an/a
Nektar Therapeutics NKTRUnited States$1.27B-54%-27%-239%13.3×n/an/a
PYC Therapeutics PYC.AXAustralia$1.28B+31%n/an/an/an/an/a
Celltrion Pharm 068760.KSSouth Korea$1.27B-29%+14%11%3.0×11.7%+18.1%
Avalyn Pharma AVLNUnited States$1.29B+7%n/an/an/an/an/a
OliX Pharmaceuticals 226950.KSSouth Korea$1.26B-57%+81%-305%111.4×n/an/a
MannKind MNKDUnited States$1.25B+11%+30%3%4.0×n/an/a
Voronoi 310210.KSSouth Korea$1.31B-66%+24%-1,947%417.6×n/an/a
Sinopep-Allsino Bio Pharmaceutical 688076.SSChina$1.31B-7%+14%19%5.0×4.0%+27.9%
C.Q. Pharmaceutical 000950.SZChina$1.32B-12%-3%1%0.5×n/an/a
Tianjin Chase Sun Pharmaceutical 300026.SZChina$1.32B-6%-29%3%2.0×8.5%-5.3%
Omeros OMERUnited States$1.22B+14%n/a-190%36.2×n/an/a
Hanall Biopharma 009420.KSSouth Korea$1.34B-25%+5%3%11.2×n/an/a
Lotus Pharmaceutical 1795.TWTaiwan$1.34B-26%+49%24%3.4×-2.4%+13.8%
Everest Medicines 1952.HKHong Kong$1.22B-20%+193%-5%3.5×n/an/a
Idorsia IDIA.SWSwitzerland$1.34B-5%-5%-70%10.7×n/an/a
Zhejiang Xianju Pharmaceutical 002332.SZChina$1.34B+2%+8%11%2.1×0.3%-1.3%
Chongqing Genrix Biopharmaceutical 688443.SSChina$1.34B-10%+256%-27%10.0×n/an/a
Phibro Animal Health PAHCUnited States$1.34B-18%+17%13%1.4×-7.4%+12.7%
Shanghai OPM Biosciences 688293.SSChina$1.35B+26%+133%11%9.8×26.1%+23.1%

Questions

Who are GH Research's main competitors?
Named competitors: Compass Pathways (CMPS), atai Life Sciences (ATAI), Johnson & Johnson (esketamine) (JNJ). The cockpit's measured peer set (industry) also includes D&D Pharmatech (347850.KS), Nektar Therapeutics (NKTR), PYC Therapeutics (PYC.AX), Celltrion Pharm (068760.KS), Avalyn Pharma (AVLN), OliX Pharmaceuticals (226950.KS).
How has GH Research stock performed?
Over six months to 6 Nov 2026 the shares returned -13.1% against -10.9% for the median peer; over one year +36.9%.

How these numbers are made. Returns are close-to-close in local currency. Revenue growth and margins are trailing twelve months. Req g is the revenue growth that today's enterprise value requires for seven years at the company's own cost of capital; Delivered g is what it actually grew; the gap is the hurdle (honest precision about ±8 points, so read the ranking more than the decimal). No fair values, price targets or analyst ratings are shown, by design. Method and validation.